Background Reverse-transcription polymerase chain reaction (RT-PCR) has become the
primary method to diagnose viral diseases, including severe acute respiratory syndrome …

Figure 1 shows a schematic of the pattern of antibody response to SARS-CoV-2 infection.
Although immunoglobulin M (IgM) and immunoglobulin A (IgA) antibodies are widely regarded …

Background Influenza vaccine effectiveness (VE) is generally interpreted in the context of
vaccine match/mismatch to circulating strains with evolutionary drift in the latter invoked to …

Context Children and adolescents appear to play an important role in the transmission of
influenza. Selectively vaccinating youngsters against influenza may interrupt virus transmission …

The isolation of human coronavirus NL63 (HCoV-NL63) in The Netherlands raised questions
about its contribution to respiratory illness. In this study, a total of 525 respiratory specimens…

Human metapneumovirus (hMPV), a newly discovered paramyxovirus, has been associated
with acute respiratory tract infections (ARIs) ranging from upper ARIs to severe bronchiolitis …

Background In 2022, there were outbreaks of Mpox where the disease is not endemic. We
summarised and compared the findings from published observational studies on the clinical …

BACKGROUND: The role of children in the transmission and community spread of severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is unclear. We aimed to quantify the …

Background. We estimate vaccine effectiveness (VE) against both influenza A/subtypes and
B/lineages in Canada for the 2011–2012 trivalent inactivated influenza vaccine (TIV) with …

Background Most pediatric adenovirus respiratory infections are mild and indistinguishable
from other viral causes. However, in a few children, the disease can be severe and result in …