Epigenetic modifications, including DNA methylation, represent a potential mechanism for
environmental impacts on human disease. Maternal smoking in pregnancy remains an …

Background— DNA methylation leaves a long-term signature of smoking exposure and is one
potential mechanism by which tobacco exposure predisposes to adverse health outcomes…

DNA methylation data have become a valuable source of information for biomarker development,
because, unlike static genetic risk estimates, DNA methylation varies dynamically in …

Pre-pregnancy maternal obesity is associated with adverse offspring outcomes at birth and
later in life. Individual studies have shown that epigenetic modifications such as DNA …

Background: Characterization of the epigenome is a primary interest for children’s
environmental health researchers studying the environmental influences on human populations, …

Epigenome-wide association studies (EWAS) seek to quantify associations between traits/exposures
and DNA methylation measured at thousands or millions of CpG sites across the …

Background DNA methylation is an important epigenetic mark that can potentially link early
life exposures to adverse health outcomes later in life. Host factors like sex and age strongly …

Organophosphate pesticides are widely used and recent studies suggest associations of in
utero exposures with adverse birth outcomes and neurodevelopment. Few studies have …

Birthweight is associated with health outcomes across the life course, DNA methylation may
be an underlying mechanism. In this meta-analysis of epigenome-wide association studies …

Epigenetics refers to mitotically heritable changes to the DNA, which do not affect the DNA
sequence, but can influence its function. Currently, DNA methylation is the most studied …