User profiles for Pavel Kielkowski
Pavel KielkowskiLMU München Verified email at tum.de Cited by 589 |
5-Substituted pyrimidine and 7-substituted 7-deazapurine dNTPs as substrates for DNA polymerases in competitive primer extension in the presence of natural dNTPs
H Cahová, A Panattoni, P Kielkowski… - ACS Chemical …, 2016 - ACS Publications
A complete series of 5-substituted uracil or cytosine, as well as 7-substituted 7-deazaadenine
and 7-deazaguanine 2′-deoxyribonucleoside triphosphates (dNTPs) bearing …
and 7-deazaguanine 2′-deoxyribonucleoside triphosphates (dNTPs) bearing …
7‐Aryl‐7‐deazaadenine 2′‐deoxyribonucleoside triphosphates (dNTPs): better substrates for DNA polymerases than dATP in competitive incorporations
A series of 7‐substituted 7‐deazaadenine and 5‐substituted cytosine 2′‐deoxyribonucleoside
triphosphates (dNTPs) were tested for their competitive incorporations (in the presence …
triphosphates (dNTPs) were tested for their competitive incorporations (in the presence …
[HTML][HTML] Extracellular LGALS3BP regulates neural progenitor position and relates to human cortical complexity
Basal progenitors (BPs), including intermediate progenitors and basal radial glia, are
generated from apical radial glia and are enriched in gyrencephalic species like humans, …
generated from apical radial glia and are enriched in gyrencephalic species like humans, …
[HTML][HTML] FICD activity and AMPylation remodelling modulate human neurogenesis
P Kielkowski, IY Buchsbaum, VC Kirsch… - Nature …, 2020 - nature.com
Posttranslational modification (PTM) of proteins represents an important cellular mechanism
for controlling diverse functions such as signalling, localisation or protein–protein …
for controlling diverse functions such as signalling, localisation or protein–protein …
ECE 2 regulates neurogenesis and neuronal migration during human cortical development
IY Buchsbaum, P Kielkowski, G Giorgio, AC O'Neill… - EMBO …, 2020 - embopress.org
During embryonic development, excitatory projection neurons migrate in the cerebral cortex
giving rise to organised layers. Periventricular heterotopia ( PH ) is a group of aetiologically …
giving rise to organised layers. Periventricular heterotopia ( PH ) is a group of aetiologically …
Selective activation of human caseinolytic protease P (ClpP)
…, M Gersch, A Pahl, P Kielkowski… - Angewandte Chemie …, 2018 - Wiley Online Library
Caseinolytic protease P (ClpP) is the proteolytic component of the ClpXP protein
degradation complex. Eukaryotic ClpP was recently found to act within the mitochondria‐specific …
degradation complex. Eukaryotic ClpP was recently found to act within the mitochondria‐specific …
Transient and switchable (triethylsilyl) ethynyl protection of DNA against cleavage by restriction endonucleases
P Kielkowski, H Macíčková‐Cahová, R Pohl… - Angewandte Chemie, 2011 - infona.pl
Eingeschränkter Zugang zu DNA: (Triethylsilyl)ethinyl‐modifiziertes 7‐desaza‐dATP kann
durch Primer‐Verlängerung oder Polymerase‐Kettenreaktion mit KOD XL‐Polymerase in …
durch Primer‐Verlängerung oder Polymerase‐Kettenreaktion mit KOD XL‐Polymerase in …
A pronucleotide probe for live‐cell imaging of protein AMPylation
P Kielkowski, IY Buchsbaum, T Becker, K Bach… - …, 2020 - Wiley Online Library
Conjugation of proteins to AMP (AMPylation) is a prevalent post‐translational modification (PTM)
in human cells, involved in the regulation of unfolded protein response and neural …
in human cells, involved in the regulation of unfolded protein response and neural …
[PDF][PDF] From young to old: AMPylation hits the brain
Protein post-translational modifications (PTMs) are implicated in numerous physiological
processes and significantly contribute to complex regulatory networks of protein functions. …
processes and significantly contribute to complex regulatory networks of protein functions. …
Synthesis of acetylene linked double-nucleobase nucleos (t) ide building blocks and polymerase construction of DNA containing cytosines in the major groove
P Kielkowski, R Pohl, M Hocek - The Journal of organic chemistry, 2011 - ACS Publications
(Cytosin-5-yl)ethynyl derivatives of pyrimidine and 7-deazaadenine 2-deoxyribonucleosides
and nucleoside triphosphates (dNTPs) were prepared in one step by the aqueous …
and nucleoside triphosphates (dNTPs) were prepared in one step by the aqueous …