User profiles for Pawan Upadhyay

Pawan Upadhyay, Ph.D.

- Verified email at illumina.com - Cited by 631

Pawan Upadhyay

- Verified email at iastate.edu - Cited by 291

Pawan Upadhyay

- Verified email at jiit.ac.in - Cited by 77

Modeling urban floods and drainage using SWMM and MIKE URBAN: a case study

DS Bisht, C Chatterjee, S Kalakoti, P Upadhyay… - Natural hazards, 2016 - Springer
To avoid the nuisance of frequent flooding during rainy season, designing an efficient
stormwater drainage system has become the need of the hour for present world engineers and …

[HTML][HTML] Frequency of EGFR Mutations in 907 Lung Adenocarcioma Patients of Indian Ethnicity

…, A Joshi, A Thavamani, P Chandrani, P Upadhyay… - PloS one, 2013 - journals.plos.org
Background During the past decade, the incidence of EGFR mutation has been shown to
vary across different ethnicities. It occurs at the rate of 10–15% in North Americans and …

Circulating nucleic acids damage DNA of healthy cells by integrating into their genomes

…, A Singh, A Iyer, A Singh, P Upadhyay… - Journal of …, 2015 - Springer
Whether nucleic acids that circulate in blood have any patho-physiological functions in the
host have not been explored. We report here that far from being inert molecules, circulating …

[HTML][HTML] MYOD1 (L122R) mutations are associated with spindle cell and sclerosing rhabdomyosarcomas with aggressive clinical outcomes

B Rekhi, P Upadhyay, MP Ramteke, A Dutt - Modern Pathology, 2016 - Elsevier
Recurrent mutations in the myogenic transcription factor MYOD1 and PIK3CA were initially
described in a subset of embryonal rhabdomyosarcomas. Recently, two independent studies …

[HTML][HTML] What motivates open defecation? A qualitative study from a rural setting in Nepal

…, M Bhattachan, J Thapa, AK Sunny, P Upadhyaya… - PloS one, 2019 - journals.plos.org
Introduction Open defecation is ongoing in Nepal despite the rise in efforts for increasing
latrine coverage and its use. Understanding the reasons for open defecation would …

[HTML][HTML] Cell-free chromatin from dying cancer cells integrate into genomes of bystander healthy cells to induce DNA damage and inflammation

…, A Gaikwad, N Gardi, R Chaubal, P Upadhyay… - Cell Death …, 2017 - nature.com
Bystander cells of the tumor microenvironment show evidence of DNA damage and inflammation
that can lead to their oncogenic transformation. Mediator (s) of cell–cell communication …

[HTML][HTML] Coherent convolution neural network based retinal disease detection using optical coherence tomographic images

PK Upadhyay, S Rastogi, KV Kumar - Journal of King Saud University …, 2022 - Elsevier
An optical coherence tomography images are used to visualize the retinal micro-architecture
and perform an easy scan of its abnormalities. In this paper, a coherent convolutional …

[HTML][HTML] Genomic characterization of tobacco/nut chewing HPV-negative early stage tongue tumors identify MMP10 as a candidate to predict metastases

P Upadhyay, N Gardi, S Desai, P Chandrani, A Joshi… - Oral Oncology, 2017 - Elsevier
Objectives Nodal metastases status among early stage tongue squamous cell cancer
patients plays a decisive role in the choice of treatment, wherein about 70% patients can be …

[HTML][HTML] Notch pathway activation is essential for maintenance of stem-like cells in early tongue cancer

P Upadhyay, S Nair, E Kaur, J Aich, P Dani… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Background Notch pathway plays a complex role depending on cellular contexts: promotes
stem cell maintenance or induces terminal differentiation in potential cancer-initiating cells; …

[HTML][HTML] Role of miR-944/MMP10/AXL- axis in lymph node metastasis in tongue cancer

…, A Butle, A Pal, S Desai, P Upadhyay… - Communications …, 2023 - nature.com
Occult lymph-node metastasis is a crucial predictor of tongue cancer mortality, with an
unmet need to understand the underlying mechanism. Our immunohistochemical and real-time …