[HTML][HTML] Down-regulation of IKKβ expression in glioma-infiltrating microglia/macrophages is associated with defective inflammatory/immune gene responses in …

J Mieczkowski, M Kocyk, P Nauman, K Gabrusiewicz… - Oncotarget, 2015 - ncbi.nlm.nih.gov
Glioblastoma (GBM) is an aggressive malignancy associated with profound host
immunosuppression. Microglia and macrophages infiltrating GBM acquire the pro-tumorigenic, M2 …

Microlesion effect as a predictor of the effectiveness of subthalamic deep brain stimulation for Parkinson's disease

T Tykocki, P Nauman, H Koziara… - Stereotactic and functional …, 2013 - karger.com
Background: Microlesion effect (MLE) is a commonly observed phenomenon after electrode
insertion into the subthalamic nucleus (STN) for deep brain stimulation (DBS). Objectives: …

[HTML][HTML] Exploring novel therapeutic opportunities for glioblastoma using patient-derived cell cultures

…, R Czepko, M Banach, B Czapski, P Nauman… - Cancers, 2023 - mdpi.com
Simple Summary Glioblastomas (GBM) are aggressive brain tumors with poor prognosis
that need effective treatment. GBMs are characterized by extensive cellular and molecular …

Targeted sequencing of cancer‐related genes reveals a recurrent TOP2A variant which affects DNA binding and coincides with global transcriptional changes in …

…, W Kloc, P Nauman… - … journal of cancer, 2023 - Wiley Online Library
High‐grade gliomas are aggressive, deadly primary brain tumors. Median survival of patients
with glioblastoma (GBM, WHO grade 4) is 14 months and <10% of patients survive 2 years. …

Cytokines in the pathogenesis of hemophilic arthropathy

P Wojdasiewicz, ŁA Poniatowski, P Nauman… - Cytokine & growth factor …, 2018 - Elsevier
Hemophilic arthropathy (HA) is one of the most common and typical manifestation in the
course of recurrent bleeding episodes in patients with hemophilia. Clinical and subclinical joint …

[PDF][PDF] The concentration of thyroid hormones and activities of iodothyronine deiodinases are altered in human brain gliomas

P Nauman, W Bonicki, R Michalik, A Warzecha… - Folia …, 2004 - Citeseer
We have determined the cellular concentration of thyroxine (T4) and triiodothyronine (T3)
and the activities of two brain iodothyronine deiodinases, type II (5’-D2) and type III (5-D3), in …

[PDF][PDF] Pedunculopontine nucleus deep brain stimulation in Parkinson's disease

T Tykocki, T Mandat, P Nauman - Archives of Medical Science, 2011 - termedia.pl
Postural instability and gait difficulty (PIGD) are commonly observed in advanced Parkinson’s
disease. The neuronal mechanism of PIGD is not fully understood. Dysfunction of the …

[HTML][HTML] Gliosarcoma is driven by alterations in PI3K/Akt, RAS/MAPK pathways and characterized by collagen gene expression signature

…, K Wojnicki, M Maleszewska, SS Mondal, P Nauman… - Cancers, 2019 - mdpi.com
Gliosarcoma is a very rare brain tumor reported to be a variant of glioblastoma (GBM), IDH-wildtype.
While differences in molecular and histological features between gliosarcoma and …

[PDF][PDF] State of the art paper Deep brain stimulation for refractory epilepsy

…, A Kornakiewicz, H Koziara, P Nauman - Archives of Medical …, 2012 - termedia.pl
Deep brain stimulation (DBS) is a method of treatment utilized to control medically refractory
epilepsy (RE). Patients with medically refractory epilepsy who do not achieve satisfactory …

Fluorescence-guided resection of primary and recurrent malignant gliomas with 5-aminolevulinic acid. Preliminary results

…, R Michalik, W Bonicki, P Nauman - … i neurochirurgia polska, 2012 - journals.viamedica.pl
Background and purpose Extent of resection plays a key role in the treatment of malignant
gliomas (MGs). Patients with complete glioma removal, followed by chemoradiation, obtain …