Purpose: We report efficacy and safety of 90 Y-labeled FAPI-46 ( 90 Y-FAPI-46-RLT) in
patients with advanced sarcoma, pancreatic cancer, and other cancer entities. Experimental …

Fibroblast activation protein (FAP) is overexpressed in several solid tumors and therefore
represents an attractive target for radiotheranostic applications. Recent investigations …

Prostate-specific membrane antigen (PSMA)-directed radioligand therapy (RLT) prolongs
overall survival in men with metastatic castration-resistant prostate cancer (mCRPC). However…

Hepatocellular carcinoma (HCC) is the sixth most prevalent cancer and the third most
frequent cause of cancer-related death. A growing number of local and systemic therapies are …

Calcium phosphate nanoparticles were covalently surface-functionalized with the ligand
DOTA and loaded with the radioisotope 68 Ga. The biodistribution of such 68 Ga-labelled …

Introduction Transthyretin (ATTR) amyloidosis is responsible for the majority of cardiac
amyloidosis (CA) cases and can be reliably diagnosed with bone scintigraphy and the visual …

Radioguidance that makes use of β-emitting radionuclides is gaining in popularity and could
have potential to strengthen the range of existing radioguidance techniques. While there is …

Sexual activity and/or reproduction are associated with a doubling of life expectancy in the
long-lived rodent genus Fukomys. To investigate the molecular mechanisms underlying this …

Our objective was to assess the feasibility and accuracy of Cerenkov luminescence imaging
(CLI) for assessment of surgical margins intraoperatively during radical prostatectomy. …

Background The superior accuracy and sensitivity of 18 F-FDG-PET/CT in comparison to
morphological imaging alone leads to an upstaging in up to 30% of lymphoma patients. Novel …