[PDF][PDF] MINDY-1 is a member of an evolutionarily conserved and structurally distinct new family of deubiquitinating enzymes

SAA Rehman, YA Kristariyanto, SY Choi, PJ Nkosi… - Molecular cell, 2016 - cell.com
Deubiquitinating enzymes (DUBs) remove ubiquitin (Ub) from Ub-conjugated substrates to
regulate the functional outcome of ubiquitylation. Here we report the discovery of a new …

A toolbox of stable integration vectors in the fission yeast Schizosaccharomyces pombe

A Vještica, M Marek, PJ Nkosi, L Merlini… - Journal of cell …, 2020 - journals.biologists.com
Schizosaccharomyces pombe is a widely used model organism to study many aspects of
eukaryotic cell physiology. Its popularity as an experimental system partially stems from the …

[PDF][PDF] Tethering of SCFDia2 to the replisome promotes efficient ubiquitylation and disassembly of the CMG helicase

T Maculins, PJ Nkosi, H Nishikawa, K Labib - Current Biology, 2015 - cell.com
Disassembly of the Cdc45-MCM-GINS (CMG) DNA helicase, which unwinds the parental
DNA duplex at eukaryotic replication forks, is the key regulated step during replication …

The Mitotic Exit Network and Cdc14 phosphatase initiate cytokinesis by counteracting CDK phosphorylations and blocking polarised growth

A Sanchez‐Diaz, PJ Nkosi, S Murray, K Labib - The EMBO journal, 2012 - embopress.org
Polarisation of the actin cytoskeleton must cease during cytokinesis, to support efficient
assembly and contraction of the actomyosin ring at the site of cell division, but the underlying …

Gamete fusion triggers bipartite transcription factor assembly to block re-fertilization

A Vještica, L Merlini, PJ Nkosi, SG Martin - Nature, 2018 - nature.com
The ploidy cycle, which is integral to sexual reproduction, requires meiosis to halve
chromosome numbers as well as mechanisms that ensure zygotes are formed by exactly two …

[HTML][HTML] Hof1 and Rvs167 have redundant roles in actomyosin ring function during cytokinesis in budding yeast

PJ Nkosi, BS Targosz, K Labib, A Sanchez-Diaz - PloS one, 2013 - journals.plos.org
The Hof1 protein (Homologue of Fifteen) regulates formation of the primary septum during
cytokinesis in the budding yeast Saccharomyces cerevisiae, whereas the orthologous Cdc15 …

[HTML][HTML] Cell cycle-dependent and independent mating blocks ensure fungal zygote survival and ploidy maintenance

A Vještica, M Berard, G Liu, L Merlini, PJ Nkosi… - PLoS …, 2021 - journals.plos.org
… Genetic crosses were performed by mixing freshly streaked strains on either ME or MSL −N
media. We note that MSL −N media enhanced mating and sporulation of mutants lacking …

Fungal zygote survival and ploidy maintenance rely on cell cycle-dependent and independent mating blocks

A Vještica, M Bérard, G Liu, L Merlini, PJ Nkosi… - bioRxiv, 2020 - biorxiv.org
… Genetic crosses were performed by mixing freshly streaked strains on either ME or MSL -N
media. We note that MSL-N media enhanced mating and sporulation of mutants lacking …

Gamete fusion rapidly reconstitutes a bi-partite transcription factor to block re-fertilization

A Vještica, L Merlini, P N'kosi, SG Martin - bioRxiv, 2018 - biorxiv.org
The ploidy cycle, integral to sexual reproduction, requires not only meiosis to halve the
number of chromosomes, but also mechanisms that ensure zygotes are formed by exactly two …

Hof1 and Rvs167 Have Redundant Roles in Actomyosin Ring Function during Cytokinesis in Budding Yeast

P Junior Nkosi, BS Targosz, K Labib, A Sánchez Díaz - 2013 - repositorio.unican.es
The Hof1 protein (Homologue of Fifteen) regulates formation of the primary septum during
cytokinesis in the budding yeast Saccharomyces cerevisiae, whereas the orthologous Cdc15 …