Human monocytes differentiate into dendritic cells (DCs) or macrophages according to the
nature of environmental signals. Monocytes stimulated with granulocyte-macrophage colony-…

Metal overload plays an important role in several diseases or intoxications, like in Wilson’s
disease, a major genetic disorder of copper metabolism in humans. To efficiently and …

Silver nanoparticles (AgNPs) can enter eukaryotic cells and exert toxic effects, most probably
as a consequence of the release of Ag+ ions. Due to the elusive nature of Ag+ ionic species…

Copper oxide nanoparticles (CuO-NP) were studied for their toxicity and mechanism of action
on hepatocytes (HepG2), in relation to Cu homeostasis disruption. Indeed, hepatocytes, in …

Liver cells are an essential target for drug delivery in many diseases. The hepatocytes express
the asialoglycoprotein receptor (ASGPR), which promotes specific uptake by means of N‐…

The impact on human health of long-term exposure to low doses of silver nanoparticles (AgNPs)
remains understudied. Cellular studies have shown the intracellular dissolution of …

Silver nanoparticles (AgNP) are heavily used in consumer products and medical devices,
including face masks to fight against COVID-19. AgNP effects on mammals have been studied …

The SOUL, or heme-binding protein HBP/SOUL, family represents a group of evolutionary
conserved putative heme-binding proteins that contains a number of members in animal, plant …

Germline specific point mutations in the gene encoding fibroblast growth factor receptor 3 (FGFR3)
are associated with autosomal dominant human skeletal dysplasia and …

Outer membrane protein A (OmpA) is a class of bacterial cell wall protein that is immunogenic
without adjuvant. As specific immune responses are initiated in the lymph nodes (LN), we …