Tumor necrosis factor-α (TNFα) and nitric oxide (NO), the product of inducible NO synthase (iNOS),
mediate inflammatory and immune responses in the CNS under a variety of …

Inefficient knock-in of transgene cargos limits the potential of cell-based medicines. In this
study, we used a CRISPR nuclease that targets a site within an exon of an essential gene and …

Tissue-resident memory T (T RM ) cells have been widely characterized in infectious disease
settings; however, their role in mediating immunity to cancer remains unknown. We report …

: Oxidative stress is known to induce cell death in a wide variety of cell types, apparently by
modulating intracellular signaling pathways. In this study, we have examined the activation of …

Objective: The purpose of this study was to characterize the oxytocin-induced desensitization
of oxytocin-stimulated rises of intracellular calcium in cultured human myocytes. Study …

Combinatorial use of iron oxide nanoparticles (IONPs) and an alternating magnetic field (AMF)
can induce local hyperthermia in tumors in a controlled and uniform manner. Heating B16 …

While T-cell responses to cancer immunotherapy have been avidly studied, long-lived
memory has been poorly characterized. In a cohort of metastatic melanoma survivors with …

The development of effective method for monitoring of endogenous hypochlorous acid (HClO)
in vivo is of great significance for early diagnosis of lipopolysaccharide (LPS) induced …

The nature of the anti-tumor immune response changes as primary tumors progress and
metastasize. We investigated the role of resident memory (Trm) and circulating memory (Tcirm) …

Rationally developing an intelligent tool for high-contrast fluorescence imaging of latent
fingerprints (LFPs) is gaining much concern in many applications such as medical diagnostics …