[HTML][HTML] Ciliary Hedgehog signaling patterns the digestive system to generate mechanical forces driving elongation

Y Yang, P Paivinen, C Xie, AL Krup, TP Makela… - Nature …, 2021 - nature.com
How tubular organs elongate is poorly understood. We found that attenuated ciliary Hedgehog
signaling in the gut wall impaired patterning of the circumferential smooth muscle and …

LKB1 represses ATOH1 via PDK4 and energy metabolism and regulates intestinal stem cell fate

…, S Tripathi, N Pentinmikko, A Amaral, P Päivinen… - Gastroenterology, 2020 - Elsevier
Pekka Päivinen performed the immunohistochemical staining for LKB1 and PDK4 and …
Pekka Päivinen provided constructive advice and revised the manuscript with important …

Inactivation of AMPK leads to attenuation of antigen presentation and immune evasion in lung adenocarcinoma

Y Gao, P Päivinen, S Tripathi… - Clinical Cancer …, 2022 - AACR
Purpose: Mutations in STK11 (LKB1) occur in 17% of lung adenocarcinoma (LUAD) and
drive a suppressive (cold) tumor immune microenvironment (TIME) and resistance to …

Ciliary signaling-patterned smooth muscle drives tubular elongation

Y Yang, P Paivinen, C Xie, AL Krup, TP Makela… - bioRxiv, 2020 - biorxiv.org
During development, many tubular organs undergo extensive longitudinal growth to reach
their defined length, essential for their function, but how they lengthen is poorly understood. …

LKB1, AMPK and AMPK-Related Kinases Regulate Fibroblast Metabolism and Mitochondrial Biogenesis Contributing to Cancer-Associated Fibroblast Transformation

P Päivinen - 2020 - helda.helsinki.fi
LKB1, AMPK ja AMPK-sukuiset kinaasit säätelevät fibroblastien metaboliaa ja
mitokondrioiden biogeneesiä, jotka ovat yhteydessä syövän fibroblastien aktivoitumiseen. …

Collecting Visual Analogue Scales and health assessment of patients with Rheumatoid Arthritis and Ankylosing Spondylitis using an USB controller

J Suhonen, K Haataja, N Paivinen… - 2008 4th IEEE/IFIP …, 2008 - ieeexplore.ieee.org
In this paper, an electronical solution for collecting visual analogue scales (VAS) and health
assessment using an universal serial bus (USB) controller is introduced. Our novel device is …

The effect of interference in the operation of ZigBee and Bluetooth robot cars

J Suhonen, K Haataja, N Paivinen… - 2008 4th IEEE/IFIP …, 2008 - ieeexplore.ieee.org
In this paper, the noise resistance of two wireless robot cars is analyzed empirically. ZigBee
and Bluetooth robot cars are driven remotely under interference conducted by microwave …

Fibroblast-derived EGF ligand neuregulin 1 induces fetal-like reprogramming of the intestinal epithelium without supporting tumorigenic growth

TT Lemmetyinen, EW Viitala… - Disease Models & …, 2023 - journals.biologists.com
Growth factors secreted by stromal fibroblasts regulate the intestinal epithelium. Stroma-derived
epidermal growth factor (EGF) family ligands are implicated in epithelial regeneration …

[PDF][PDF] Climate change and range shifts in two insect defoliators: gypsy moth and nun moth-a model study

H Vanhanen, TO Veteli, S Paivinen, S Kellomaki… - Silva …, 2007 - researchgate.net
Environmental factors influenced by global climate change determine the distribution ranges
of organisms. Especially ectothermic animals are expected to shift their distribution ranges …

Framework for assessing and reversing ecosystem degradation–Report of the Finnish restoration prioritization working group on the options and costs of meeting the …

JS Kotiaho, S Kuusela, E Nieminen, J Päivinen… - 2016 - julkaisut.valtioneuvosto.fi
This report is an abridged and revised English language edition of the original proposition of
the Finnish restoration prioritization working group on the options and costs of restoring 15 …