A molecular water oxidation catalyst based on the copper complex of general formula [(L py
)Cu II ] 2– , 2 2– , (L py is 4-pyrenyl-1,2-phenylenebis(oxamidate) ligand) has been rationally …

Signal transduction across biological membranes is among the most important evolutionary
achievements. Herein, for the design of artificial cells, we engineer fully synthetic receptors …

We present three classes of chemical zymogens established around the protein cysteinome.
In each case, the cysteine thiol group was converted into a mixed disulfide: with a small …

Nanozymes can mimic the activities of diverse enzymes, and this ability finds applications in
analytical sciences and industrial chemistry, as well as in biomedical applications. Among …

A vast range of biomedical applications relies on the specificity of interactions between an
antigen and its cognate receptor or antibody. This specificity can be highest when said …

The design of a fully synthetic, chemical “apoptosis‐inducing receptor” (AIR) molecule is
reported that is anchored into the lipid bilayer of cells, is activated by the incoming biological …

The newest generation of cell‐based technologies relies heavily on methods to communicate
to the engineered cells using artificial receptors, specifically to deactivate the cells …

Macromolecular prodrugs (MP) built on the natural phosphodiester and deoxyribose
backbone are developed using marketed antiviral nucleoside analogues. These MP are …

Chemical zymogens of three different types were established herein around protein
cysteinome, in each case converting the protein thiol into a disulfide linkage: zero length Z 0 , …

Chemical glycosylation of proteins is a powerful tool applied widely in biomedicine and
biotechnology. However, it is a challenging undertaking and typically relies on recombinant …