Results Plasma levels of IL-1β, IL-1RA, IL-6, TNF-α, hs-CRP, and fibrinogen were higher
among participants with lower levels of eGFR. Inflammation score was higher among those with …

This article provides an overview of the current literature on seven cancer sites that may
disproportionately affect lesbian, gay, bisexual, transgender/transsexual, and queer/questioning …

We report a genome-wide association study of melanoma conducted by the GenoMEL
consortium based on 317K tagging SNPs for 1,650 selected cases and 4,336 controls, with …

Background: The major factors individually reported to be associated with an increased
frequency of CDKN2A mutations are increased number of patients with melanoma in a family, …

GenoMEL, comprising major familial melanoma research groups from North America,
Europe, Asia, and Australia has created the largest familial melanoma sample yet available to …

Germline variants in MC1R, the gene encoding the melanocortin-1 receptor, and sun exposure
increase risk for melanoma in Caucasians. The majority of melanomas that occur on skin …

Testicular germ cell tumors (TGCT) have been expected to have a strong underlying genetic
component. We conducted a genome-wide scan among 277 TGCT cases and 919 controls …

Background Melanoma risk is related to sun exposure; we have investigated risk variation
by tumour site and latitude. Methods We performed a pooled analysis of 15 case–control …

Importance This study proposes an alternative tumor staging system for cutaneous squamous
cell carcinoma (CSCC) that more precisely defines the small subset of tumors with a high …

We report a genome-wide association study for melanoma that was conducted by the GenoMEL
Consortium. Our discovery phase included 2,981 individuals with melanoma and 1,982 …