Poor outcomes in COVID‐19 correlate with clinical and laboratory features of cytokine storm
syndrome. Broad screening for cytokine storm and early, targeted antiinflammatory therapy …

In addition to their pivotal role in thrombosis and wound repair, platelets participate in
inflammatory responses. We investigated the role of platelets in the autoimmune disease …

CD4 + T cells are central mediators of autoimmune pathology; however, defining their key
effector functions in specific autoimmune diseases remains challenging. Pathogenic CD4 + T …

BACKGROUND Pediatric SARS–CoV-2 infection can be complicated by a dangerous
hyperinflammatory condition termed multisystem inflammatory syndrome in children (MIS-C). The …

Mitochondrial DNA (mtDNA) is a highly potent inflammatory trigger and is reportedly found
outside the cells in blood in various pathologies. Platelets are abundant in blood where they …

A bacterial etiology of rheumatoid arthritis (RA) has been suspected since the beginnings of
modern germ theory. Recent studies implicate mucosal surfaces as sites of disease initiation…

… Nigrovic had full access to all of the data in the study and takes responsibility for the integrity
… Nigrovic regarding statistics, and the involvement of the following physicians in the care of …

Objective To provide updated guidelines for pharmacologic management of juvenile
idiopathic arthritis (JIA), focusing on treatment of oligoarthritis, temporomandibular joint (TMJ) …

The American College of Rheumatology (ACR) published treatment recommendations for
juvenile idiopathic arthritis (JIA) in 2011 (1). These recommendations represented the first …

We used the Immunochip array to analyze 2,816 individuals with juvenile idiopathic arthritis
(JIA), comprising the most common subtypes (oligoarticular and rheumatoid factor–negative …