User profiles for Peter J. Harding
Peter J HardingManchester Metropolitan University Verified email at mmu.ac.uk Cited by 304 |
[HTML][HTML] Constitutive dimerization of the G-protein coupled receptor, neurotensin receptor 1, reconstituted into phospholipid bilayers
PJ Harding, H Attrill, J Boehringer, S Ross… - Biophysical …, 2009 - cell.com
Neurotensin receptor 1 (NTS1), a Family A G-protein coupled receptor (GPCR), was expressed
in Escherichia coli as a fusion with the fluorescent proteins eCFP or eYFP. A fluorophore-…
in Escherichia coli as a fusion with the fluorescent proteins eCFP or eYFP. A fluorophore-…
Real-time ultrasound segmentation, analysis and visualisation of deep cervical muscle structure
RJ Cunningham, PJ Harding… - IEEE transactions on …, 2016 - ieeexplore.ieee.org
Despite widespread availability of ultrasound and a need for personalised muscle diagnosis
(neck/back pain-injury, work related disorder, myopathies, neuropathies), robust, online …
(neck/back pain-injury, work related disorder, myopathies, neuropathies), robust, online …
[HTML][HTML] Blunted angiogenesis and hypertrophy are associated with increased fatigue resistance and unchanged aerobic capacity in old overloaded mouse muscle
SB Ballak, T Busé-Pot, PJ Harding, MH Yap… - Age, 2016 - Springer
We hypothesize that the attenuated hypertrophic response in old mouse muscle is (1) partly
due to a reduced capillarization and angiogenesis, which is (2) accompanied by a reduced …
due to a reduced capillarization and angiogenesis, which is (2) accompanied by a reduced …
Direct analysis of a GPCR-agonist interaction by surface plasmon resonance
PJ Harding, TC Hadingham, JM McDonnell… - European Biophysics …, 2006 - Springer
Despite their clinical importance, detailed analysis of ligand binding at G-protein coupled
receptors (GPCRs) has proved difficult. Here we successfully measure the binding of a GPCR, …
receptors (GPCRs) has proved difficult. Here we successfully measure the binding of a GPCR, …
Improved yield of a ligand-binding GPCR expressed in E. coli for structural studies
H Attrill, PJ Harding, E Smith, S Ross, A Watts - Protein Expression and …, 2009 - Elsevier
The G-protein coupled receptor (GPCR), rat brain neurotensin receptor type I (NTS1) is one
of a small number of GPCRs that have been successfully expressed in Escherichia coli as a …
of a small number of GPCRs that have been successfully expressed in Escherichia coli as a …
[HTML][HTML] Foreground detection analysis of ultrasound image sequences identifies markers of motor neurone disease across diagnostically relevant skeletal muscles
K Bibbings, PJ Harding, ID Loram, N Combes… - Ultrasound in medicine …, 2019 - Elsevier
Diagnosis of motor neurone disease (MND) includes detection of small, involuntary muscle
excitations, termed fasciculations. There is need to improve diagnosis and monitoring of …
excitations, termed fasciculations. There is need to improve diagnosis and monitoring of …
The application of deep convolutional neural networks to ultrasound for modelling of dynamic states within human skeletal muscle
This paper concerns the fully automatic direct in vivo measurement of active and passive
dynamic skeletal muscle states using ultrasound imaging. Despite the long standing medical …
dynamic skeletal muscle states using ultrasound imaging. Despite the long standing medical …
An automated text mining approach for classifying mental-ill health incidents from police incident logs for data-driven intelligence
MS Haleem, L Han, PJ Harding… - 2019 IEEE international …, 2019 - ieeexplore.ieee.org
Data-driven intelligence can play a pivotal role in enhancing the effectiveness and efficiency
of police service provision. Despite of police organizations being a rich source of qualitative …
of police service provision. Despite of police organizations being a rich source of qualitative …
Prediction and mitigation of crush conditions in emergency evacuations
Several simulation environments exist for the simulation of large-scale evacuations of buildings,
ships, or other enclosed spaces. These offer sophisticated tools for the study of human …
ships, or other enclosed spaces. These offer sophisticated tools for the study of human …
An early warning method for crush
Fatal crush conditions occur in crowds with tragic frequency. Event organisers and architects
are often criticised for failing to consider the causes and implications of crush, but the reality …
are often criticised for failing to consider the causes and implications of crush, but the reality …