The fluid mosaic model of membrane structure has been revised in recent years as it has
become evident that domains of different lipid composition are present in eukaryotic and …

With phenotypic heterogeneity in whole cell populations widely recognised, the demand for
quantitative and temporal analysis approaches to characterise single cell morphology and …

Ion channels can regulate the plasma membrane potential (V m ) and cell migration as a
result of altered ion flux. However, the mechanism by which V m regulates motility remains …

Id helix-loop-helix (HLH) proteins act as global regulators of metazoan cell fate, cell growth,
and differentiation. They heterodimerize with and inhibit the DNA-binding function of …

Soluble factors are an essential means of communication between cells and their environment.
However, many molecules readily interact with extracellular matrix components, giving …

Proteins of the Leishmania hydrophilic acylated surface protein B (HASPB) family are only
expressed in infective parasites (both extra‐ and intracellular stages) and, together with the …

Background An emerging problem in the treatment of breast cancer is the increasing
incidence of metastases to the brain. Metastatic brain tumours are incurable and can cause …

The binding of human erythrocyte spectrin to large unilamellar vesicles (LUVET) formed by
the extrusion technique has been studied using fluoresceinphosphatidylethanolamine (FPE) …

The kinetoplastid parasites are responsible for three of the ten most neglected tropical
diseases as classified by the WHO. Recent advances in molecular and cellular analyses have …

Platelets are specialized anucleate cells that play a major role in hemostasis following
vessel injury. More recently, platelets have also been implicated in innate immunity and …