User profiles for Peter M. Aldridge

Peter M. Aldridge

University of Toronto
Verified email at mail.utoronto.ca
Cited by 521

Tracking the dynamics of circulating tumour cell phenotypes using nanoparticle-mediated magnetic ranking

M Poudineh, PM Aldridge, S Ahmed, BJ Green… - Nature …, 2017 - nature.com
Profiling the heterogeneous phenotypes of rare circulating tumour cells (CTCs) in whole
blood is critical to unravelling the complex and dynamic properties of these potential clinical …

[HTML][HTML] Multifunctional quantum dot DNA hydrogels

L Zhang, SR Jean, S Ahmed, PM Aldridge, X Li… - Nature …, 2017 - nature.com
Biotemplated nanomaterials offer versatile functionality for multimodal imaging, biosensing,
and drug delivery. There remains an unmet need for traceable and biocompatible …

High-throughput genome-wide phenotypic screening via immunomagnetic cell sorting

…, PM Aldridge, RS Atwal, D Philpott, M Zhang… - Nature Biomedical …, 2019 - nature.com
Genome-scale functional genetic screens are used to identify key genetic regulators of a
phenotype of interest. However, the identification of genetic modifications that lead to a …

Velocity valleys enable efficient capture and spatial sorting of nanoparticle-bound cancer cells

JD Besant, RM Mohamadi, PM Aldridge, Y Li… - Nanoscale, 2015 - pubs.rsc.org
The development of strategies for isolating rare cells from complex matrices like blood is
important for a wide variety of applications including the analysis of bloodborne cancer cells, …

Prismatic deflection of live tumor cells and cell clusters

PM Aldridge, M Mukhopadhyay, SU Ahmed, W Zhou… - ACS …, 2018 - ACS Publications
The analysis of heterogeneous subpopulations of circulating tumor cells (CTCs) is critical to
enhance our understanding of cancer metastasis and enable noninvasive cancer diagnosis …

Flow of a Boger fluid around an isolated cylinder

DF James, T Shiau, PM Aldridge - Journal of Rheology, 2016 - pubs.aip.org
… James, Terence Shiau, Peter M. Aldridge; Flow of a Boger fluid around an isolated
cylinder. Journal of Rheology 1 November 2016; 60 (6): 1137–1149. https://doi.org/10.1122/…

[PDF][PDF] Image-Reversal Soft Lithography: Fabrication of Ultrasensitive Biomolecular Detectors

TS Safaei, J Das, SS Mahshid, PM Aldridge… - Adv. Healthcare …, 2016 - light.utoronto.ca
The present work began as an effort to eliminate costly lithographic steps previously employed
in the precise definition of apertures from which NMEs are grown. Our premise was that …

Scalable, FACS-Free Genome-Wide Phenotypic Screening

B Mair, PM Aldridge, RS Atwal, SN Masud, M Zhang… - bioRxiv, 2019 - biorxiv.org
Genome-scale functional genetic screens can identify key regulators of a phenotype of
interest, such as determinants of protein expression or modification. Here, we present a rapid, …

Constructivist learning environments in a crossnational study in Taiwan and Australia

JM Aldridge, BJ Fraser, PC Taylor… - International Journal of …, 2000 - Taylor & Francis
This article focuses on the validation and use of English and Chinese versions of the
Constructivist Learning Environment Survey (CLES) in a cross-national study of high school …

Chemical modifications of biopolymers by quinones and quinone methides

MG Peter - Angewandte Chemie International Edition in English, 1989 - Wiley Online Library
… UV-spectroscopic evidence for the reaction between cysteine and various quinones was
reported first by Mason and Peter~on,"~] who studied models for melanoprotein biosynthesis, …