Evidence of human coronavirus HKU1 and human bocavirus in Australian children

TP Sloots, P McErlean, DJ Speicher, KE Arden… - Journal of clinical …, 2006 - Elsevier
Undiagnosed cases of respiratory tract disease suspected of an infectious aetiology peak
during the winter months. Since studies applying molecular diagnostic assays usually report …

Frequent detection of human rhinoviruses, paramyxoviruses, coronaviruses, and bocavirus during acute respiratory tract infections

KE Arden, P McErlean, MD Nissen… - Journal of medical …, 2006 - Wiley Online Library
Viruses are the major cause of pediatric acute respiratory tract infection (ARTI) and yet many
suspected cases of infection remain uncharacterized. We employed 17 PCR assays and …

Do rhinoviruses reduce the probability of viral co-detection during acute respiratory tract infections?

RM Greer, P McErlean, KE Arden, CE Faux… - Journal of Clinical …, 2009 - Elsevier
BACKGROUND: Human rhinoviruses (HRVs) are often concurrently detected with other
viruses found in the respiratory tract because of the high total number of HRV infections …

[HTML][HTML] Distinguishing Molecular Features and Clinical Characteristics of a Putative New Rhinovirus Species, Human Rhinovirus C (HRV C)

P McErlean, LA Shackelton, E Andrews, DR Webster… - PloS one, 2008 - journals.plos.org
Background Human rhinoviruses (HRVs) are the most frequently detected pathogens in acute
respiratory tract infections (ARTIs) and yet little is known about the prevalence, recurrence, …

The transferrin receptor CD71 delineates functionally distinct airway macrophage subsets during idiopathic pulmonary fibrosis

SJ Allden, PP Ogger, P Ghai, P McErlean… - American journal of …, 2019 - atsjournals.org
Rationale: Idiopathic pulmonary fibrosis (IPF) is a devastating progressive disease with
limited therapeutic options. Airway macrophages (AMs) are key components of the defense of …

Itaconate controls the severity of pulmonary fibrosis

…, E Calamita, P Ghai, SA Walker, P McErlean… - Science …, 2020 - science.org
Idiopathic pulmonary fibrosis (IPF) is a fatal lung disease in which airway macrophages (AMs)
play a key role. Itaconate has emerged as a mediator of macrophage function, but its role …

[HTML][HTML] Co-circulation of four human coronaviruses (HCoVs) in Queensland children with acute respiratory tract illnesses in 2004

…, KE Arden, DJ Speicher, NT O'Neil, PK McErlean… - Viruses, 2012 - mdpi.com
Acute respiratory illnesses (ARIs) with unconfirmed infectious aetiologies peak at different
times of the year. Molecular diagnostic assays reduce the number of unconfirmed ARIs …

DNA methylome alterations are associated with airway macrophage differentiation and phenotype during lung fibrosis

P McErlean, CG Bell, RJ Hewitt, Z Busharat… - American Journal of …, 2021 - atsjournals.org
Rationale: Airway macrophages (AMs) are key regulators of the lung environment and are
implicated in the pathogenesis of idiopathic pulmonary fibrosis (IPF), a fatal respiratory …

[HTML][HTML] Human rhinovirus infection causes different DNA methylation changes in nasal epithelial cells from healthy and asthmatic subjects

P McErlean, S Favoreto, FF Costa, J Shen… - BMC medical …, 2014 - Springer
Background Mechanisms underlying the development of virus-induced asthma exacerbations
remain unclear. To investigate if epigenetic mechanisms could be involved in virus-…

SOX2 drives bronchial dysplasia in a novel organotypic model of early human squamous lung cancer

LL Correia, JA Johnson, P McErlean… - American journal of …, 2017 - atsjournals.org
Rationale: Improving the early detection and chemoprevention of lung cancer are key to
improving outcomes. The pathobiology of early squamous lung cancer is poorly understood. We …