User profiles for Peter Pfaffelhuber

Peter Pfaffelhuber

Albert-Ludwigs Universität, Freiburg
Verified email at stochastik.uni-freiburg.de
Cited by 2042

The impact of sampling schemes on the site frequency spectrum in nonequilibrium subdivided populations

…, B Haubold, C Merino, W Stephan, P Pfaffelhuber - Genetics, 2009 - academic.oup.com
Using coalescent simulations, we study the impact of three different sampling schemes on
patterns of neutral diversity in structured populations. Specifically, we are interested in two …

Convergence in distribution of random metric measure spaces (Λ-coalescent measure trees)

A Greven, P Pfaffelhuber, A Winter - Probability Theory and Related Fields, 2009 - Springer
We consider the space of complete and separable metric spaces which are equipped with a
probability measure. A notion of convergence is given based on the philosophy that a …

The infinitely many genes model for the distributed genome of bacteria

…, WR Hess, P Pfaffelhuber - Genome biology and …, 2012 - academic.oup.com
The distributed genome hypothesis states that the gene pool of a bacterial taxon is much
more complex than that found in a single individual genome. However, the possible fitness …

andi: Fast and accurate estimation of evolutionary distances between closely related genomes

B Haubold, F Klötzl, P Pfaffelhuber - Bioinformatics, 2015 - academic.oup.com
Motivation: A standard approach to classifying sets of genomes is to calculate their pairwise
distances. This is difficult for large samples. We have therefore developed an algorithm for …

mlRho–a program for estimating the population mutation and recombination rates from shotgun‐sequenced diploid genomes

B Haubold, P Pfaffelhuber, M Lynch - Molecular ecology, 2010 - Wiley Online Library
Improvements in sequencing technology over the past 5 years are leading to routine
application of shotgun sequencing in the fields of ecology and evolution. However, the theory to …

Estimating mutation distances from unaligned genomes

B Haubold, P Pfaffelhuber… - Journal of …, 2009 - liebertpub.com
Alignment-free distance measures are generally less accurate but more efficient than
traditional alignment-based metrics. In the context of genome sequence analysis, the efficiency …

Europe's Roma people are vulnerable to poor practice in genetics

V Lipphardt, M Surdu, N Ellebrecht, P Pfaffelhuber… - Nature, 2021 - nature.com
Peter PfaffelhuberPeter PfaffelhuberPeter Pfaffelhuber is professor of probability
theory and modelling in the life sciences at the University of Freiburg, Germany. …

Probabilistic genetic identification of wild boar hybridization to support control of invasive wild pigs (Sus scrofa)

TJ Smyser, P Pfaffelhuber, RM Giglio, MG DeSaix… - …, 2024 - Wiley Online Library
The rapid expansion of wild pigs (Sus scrofa) throughout the United States has been fueled
by unlawful introductions, with invasive populations causing extensive crop losses, …

Tree-valued Fleming–Viot dynamics with mutation and selection

A Depperschmidt, A Greven, P Pfaffelhuber - 2012 - projecteuclid.org
The Fleming–Viot measure-valued diffusion is a Markov process describing the evolution of
(allelic) types under mutation, selection and random reproduction. We enrich this process by …

An approximate sampling formula under genetic hitchhiking

A Etheridge, P Pfaffelhuber, A Wakolbinger - 2006 - projecteuclid.org
For a genetic locus carrying a strongly beneficial allele which has just fixed in a large
population, we study the ancestry at a linked neutral locus. During this “selective sweep” the …