User profiles for Peter Pfaffelhuber
Peter PfaffelhuberAlbert-Ludwigs Universität, Freiburg Verified email at stochastik.uni-freiburg.de Cited by 2042 |
The impact of sampling schemes on the site frequency spectrum in nonequilibrium subdivided populations
…, B Haubold, C Merino, W Stephan, P Pfaffelhuber - Genetics, 2009 - academic.oup.com
Using coalescent simulations, we study the impact of three different sampling schemes on
patterns of neutral diversity in structured populations. Specifically, we are interested in two …
patterns of neutral diversity in structured populations. Specifically, we are interested in two …
Convergence in distribution of random metric measure spaces (Λ-coalescent measure trees)
A Greven, P Pfaffelhuber, A Winter - Probability Theory and Related Fields, 2009 - Springer
We consider the space of complete and separable metric spaces which are equipped with a
probability measure. A notion of convergence is given based on the philosophy that a …
probability measure. A notion of convergence is given based on the philosophy that a …
The infinitely many genes model for the distributed genome of bacteria
…, WR Hess, P Pfaffelhuber - Genome biology and …, 2012 - academic.oup.com
The distributed genome hypothesis states that the gene pool of a bacterial taxon is much
more complex than that found in a single individual genome. However, the possible fitness …
more complex than that found in a single individual genome. However, the possible fitness …
andi: Fast and accurate estimation of evolutionary distances between closely related genomes
B Haubold, F Klötzl, P Pfaffelhuber - Bioinformatics, 2015 - academic.oup.com
Motivation: A standard approach to classifying sets of genomes is to calculate their pairwise
distances. This is difficult for large samples. We have therefore developed an algorithm for …
distances. This is difficult for large samples. We have therefore developed an algorithm for …
mlRho–a program for estimating the population mutation and recombination rates from shotgun‐sequenced diploid genomes
B Haubold, P Pfaffelhuber, M Lynch - Molecular ecology, 2010 - Wiley Online Library
Improvements in sequencing technology over the past 5 years are leading to routine
application of shotgun sequencing in the fields of ecology and evolution. However, the theory to …
application of shotgun sequencing in the fields of ecology and evolution. However, the theory to …
Estimating mutation distances from unaligned genomes
B Haubold, P Pfaffelhuber… - Journal of …, 2009 - liebertpub.com
Alignment-free distance measures are generally less accurate but more efficient than
traditional alignment-based metrics. In the context of genome sequence analysis, the efficiency …
traditional alignment-based metrics. In the context of genome sequence analysis, the efficiency …
Europe's Roma people are vulnerable to poor practice in genetics
V Lipphardt, M Surdu, N Ellebrecht, P Pfaffelhuber… - Nature, 2021 - nature.com
… Peter Pfaffelhuber … Peter Pfaffelhuber … Peter Pfaffelhuber is professor of probability
theory and modelling in the life sciences at the University of Freiburg, Germany. …
theory and modelling in the life sciences at the University of Freiburg, Germany. …
Probabilistic genetic identification of wild boar hybridization to support control of invasive wild pigs (Sus scrofa)
The rapid expansion of wild pigs (Sus scrofa) throughout the United States has been fueled
by unlawful introductions, with invasive populations causing extensive crop losses, …
by unlawful introductions, with invasive populations causing extensive crop losses, …
Tree-valued Fleming–Viot dynamics with mutation and selection
A Depperschmidt, A Greven, P Pfaffelhuber - 2012 - projecteuclid.org
The Fleming–Viot measure-valued diffusion is a Markov process describing the evolution of
(allelic) types under mutation, selection and random reproduction. We enrich this process by …
(allelic) types under mutation, selection and random reproduction. We enrich this process by …
An approximate sampling formula under genetic hitchhiking
A Etheridge, P Pfaffelhuber, A Wakolbinger - 2006 - projecteuclid.org
For a genetic locus carrying a strongly beneficial allele which has just fixed in a large
population, we study the ancestry at a linked neutral locus. During this “selective sweep” the …
population, we study the ancestry at a linked neutral locus. During this “selective sweep” the …