The reversible phosphorylation of proteins on serine, threonine, and tyrosine residues is an
important biological regulatory mechanism. In the context of genome integrity, signaling …

Meiosis ensures the reduction of the genome before the formation of generative cells and
promotes the exchange of genetic information between homologous chromosomes by …

During meiosis, homologous chromosomes recognize each other, align, and exchange genetic
information. This process requires the action of RecA-related proteins Rad51 and Dmc1 …

Mutants in the PRT1 gene of Arabidopsis thaliana are impaired in the degradation of a normally
short-lived intracellular protein that contains a destabilizing N-terminal residue. Proteins …

Obligatory homologous recombination (HR) is required for chiasma formation and
chromosome segregation in meiosis I. Meiotic HR is initiated by DNA double‐strand breaks (DSBs), …

DNA double-strand break (DSB) repair depends on the ataxia telangiectasia mutated (ATM)
kinase that phosphorylates the conserved C-terminal SQ motif present in the histone variant …

All processes requiring interaction with DNA are attuned to occur within the context of the
complex chromatin structure. As it does for programmed transcription and replication, this also …

In the current meiotic recombination initiation model, the SPO11 catalytic subunits associate
with MTOPVIB to form a Topoisomerase VI-like complex that generates DNA double strand …

Meiosis is a specialized cell division in sexually reproducing organisms before gamete
formation. Following DNA replication, the canonical sequence in species with monocentric …

Despite vast differences between organisms, some characteristics of their genomes are
conserved, such as the nucleolus organizing region (NOR). The NOR is constituted of multiple, …