The eIF2α kinase heme-regulated inhibitor protects the host from infection by regulating intracellular pathogen trafficking
W Bahnan, JC Boucher, P Gayle, N Shrestha… - Infection and …, 2018 - Am Soc Microbiol
The host employs both cell-autonomous and system-level responses to limit pathogen
replication in the initial stages of infection. Previously, we reported that the eukaryotic initiation …
replication in the initial stages of infection. Previously, we reported that the eukaryotic initiation …
Maternal-and fetal-encoded perforin-2 limits placental infection by a bloodborne pathogen
P Gayle, V McGaughey, R Hernandez… - The Journal of …, 2020 - journals.aai.org
Placental immune responses are highly regulated to strike a balance between protection and
tolerance. For relatively mild infections, protection encompasses both the mother and fetus; …
tolerance. For relatively mild infections, protection encompasses both the mother and fetus; …
Using a bacterial pathogen to probe for cellular and organismic-level host responses
P Gayle, NE Freitag, N Strbo, K Schesser - JoVE (Journal of Visualized …, 2019 - jove.com
There are a variety of strategies bacterial pathogens employ to survive and proliferate once
inside the eukaryotic cell. The so-called 'cytosolic' pathogens (Listeria monocytogenes, …
inside the eukaryotic cell. The so-called 'cytosolic' pathogens (Listeria monocytogenes, …
[PDF][PDF] The Function of Perforin-2 at the Maternal-Fetal Interface
P Gayle - 2020 - scholarship.miami.edu
Placental immune responses are highly regulated to strike a balance between protection
and tolerance. During relatively mild infections, protection encompasses both the mother and …
and tolerance. During relatively mild infections, protection encompasses both the mother and …
Perforin-2 limits pathogen proliferation at the maternal-fetal interface
P Gayle, V McGaughey, R Hernandez, M Wylie… - bioRxiv, 2020 - biorxiv.org
Placental immune responses are highly regulated to strike a balance between protection and
tolerance. For relatively mild infections, protection encompasses both the mother and fetus; …
tolerance. For relatively mild infections, protection encompasses both the mother and fetus; …
The eIF2α kinase Heme Regulated Inhibitor (HRI) protects the host from infection by regulating intracellular pathogen trafficking
W Bahnan, JC Boucher, P Gayle, N Shrestha, M Rosen… - bioRxiv, 2017 - biorxiv.org
Phosphorylation of eIF2α by its kinases is a stress response universally conserved among
the eukaryota. Previously, we reported that the eIF2α kinases Heme Regulator Inhibitor (HRI) …
the eukaryota. Previously, we reported that the eIF2α kinases Heme Regulator Inhibitor (HRI) …
[BOOK][B] Development and Optimization of Kinetic Target-Guided Synthesis Approaches Targeting Protein-Protein Interactions of the Bcl-2 Family
SS Kulkarni - 2012 - search.proquest.com
… I am pleased to thank the undergraduate students, Matthew Sarnowski, Megan Barber,
Petoria Gayle, and Maylene Quiroga for their contributions to some of the research projects. …
Petoria Gayle, and Maylene Quiroga for their contributions to some of the research projects. …
The adoption and use of through-life engineering services within UK manufacturing organisations
Manufacturing organisations seek ever more innovative approaches in order to maintain
and improve their competitive position within the global market. One such initiative that is …
and improve their competitive position within the global market. One such initiative that is …
Jamaican Cenozoic Echinoidea
SK Donovan - Geological Society of America Memoirs, 1993 - pubs.geoscienceworld.org
The Jamaican Cenozoic echinoid fauna is large and diverse, comprising about 95 nominal
species (with further taxa presently classified under open nomenclature) divided between 43 …
species (with further taxa presently classified under open nomenclature) divided between 43 …