User profiles for Petr Nickl
 | Petr NicklInstitute of Molecular Genetics Verified email at img.cas.cz Cited by 165 |
[HTML][HTML] CRISPR/Cas9 epigenome editing potential for rare imprinting diseases: a review
LA Syding, P Nickl, P Kasparek, R Sedlacek - Cells, 2020 - mdpi.com
Imprinting diseases (IDs) are rare congenital disorders caused by aberrant dosages of
imprinted genes. Rare IDs are comprised by a group of several distinct disorders that share a …
imprinted genes. Rare IDs are comprised by a group of several distinct disorders that share a …
[HTML][HTML] Bispecific IgG neutralizes SARS-CoV-2 variants and prevents escape in mice
Neutralizing antibodies that target the receptor-binding domain (RBD) of the SARS-CoV-2
spike protein are among the most promising approaches against COVID-19 1 , 2 . A bispecific …
spike protein are among the most promising approaches against COVID-19 1 , 2 . A bispecific …
[HTML][HTML] Generation and Characterization of a Novel Angelman Syndrome Mouse Model with a Full Deletion of the Ube3a Gene
LA Syding, A Kubik-Zahorodna, P Nickl, V Novosadova… - Cells, 2022 - mdpi.com
Angelman syndrome (AS) is a neurodevelopmental disorder caused by deficits in maternally
inherited UBE3A. The disease is characterized by intellectual disability, impaired motor …
inherited UBE3A. The disease is characterized by intellectual disability, impaired motor …
[HTML][HTML] Advances in Modelling COVID-19 in Animals
P Nickl, MJ Raishbrook, LA Syding… - Frontiers in Drug …, 2022 - frontiersin.org
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV2) is a positive-sense-single
stranded RNA virus and the cause of the coronavirus disease 2019 (COVID-19). The World …
stranded RNA virus and the cause of the coronavirus disease 2019 (COVID-19). The World …
[HTML][HTML] Ablation of Gabra5 Influences Corticosterone Levels and Anxiety-like Behavior in Mice
LA Syding, A Kubik-Zahorodna, DP Reguera, P Nickl… - Genes, 2023 - mdpi.com
Stress responses are activated by the hypothalamic-pituitary-adrenal axis (HPA axis),
culminating in the release of glucocorticoids. During prolonged periods of secretion of …
culminating in the release of glucocorticoids. During prolonged periods of secretion of …
Publisher Correction: Bispecific IgG neutralizes SARS-CoV-2 variants and prevents escape in mice
R De Gasparo, M Pedotti, L Simonelli, P Nickl… - Nature, 2021 - nature.com
… Petr Bednar … Petr Nickl … Petr Bednar …
CRISPR technology and its potential role in treating rare imprinting diseases
P Nickl, LA Syding, R Sedlacek - Principles of Gender-Specific Medicine, 2023 - Elsevier
Genomic imprinting is an epigenetic process leading to parent-of-origin–specific silencing
of certain genes. A failure to establish appropriate expression from either the paternal or the …
of certain genes. A failure to establish appropriate expression from either the paternal or the …
Bispecific antibody prevents SARS-CoV-2 escape and protects mice from disease
R De Gasparo, M Pedotti, L Simonelli, P Nickl… - 2021 - pesquisa.bvsalud.org
Neutralizing antibodies targeting the receptor binding domain (RBD) of the SARS-CoV-2
Spike (S) are among the most promising approaches against coronavirus disease 2019 (COVID…
Spike (S) are among the most promising approaches against coronavirus disease 2019 (COVID…
Mutagenesis in Danio rerio using CRISPR technology
P Nickl - 2019 - dspace.cuni.cz
CRISPR/Cas9 technology is currently one of the most important tools of genome engineering.
This technology allows a precise site-specific gene editing and such ability was applied to …
This technology allows a precise site-specific gene editing and such ability was applied to …
Bispecific antibody neutralizes circulating SARS-CoV-2 variants, prevents escape and protects mice from disease
Neutralizing antibodies targeting the receptor binding domain (RBD) of the SARS-CoV-2
Spike (S) are among the most promising approaches against coronavirus disease 2019 (COVID…
Spike (S) are among the most promising approaches against coronavirus disease 2019 (COVID…