User profiles for Petronela Buiga

Petronela Buiga

Postdoctoral Scholar, Stanford University, School of Medicine
Verified email at stanford.edu
Cited by 81

[HTML][HTML] Premalignant SOX2 overexpression in the fallopian tubes of ovarian cancer patients: Discovery and validation studies

…, K Gaitskell, S Elorbany, R Xu, A Laios, P Buiga… - …, 2016 - thelancet.com
Current screening methods for ovarian cancer can only detect advanced disease. Earlier
detection has proved difficult because the molecular precursors involved in the natural history …

[HTML][HTML] Oral neutrophil free fatty acid receptors expression may link oral host and microbiome lipid metabolism

M Wzatek, S Bahammam, P Buiga, K Haddad… - Frontiers in Oral …, 2022 - frontiersin.org
In health, commensal bacteria from oral biofilms stimulate polymorphonuclear neutrophil (PMN)
recruitment in gingival sulci and the oral cavity. Oral PMN (oPMN) are short lived cells …

[HTML][HTML] Regulation of dual specificity phosphatases in breast cancer during initial treatment with Herceptin: A Boolean model analysis

P Buiga, A Elson, L Tabernero, JM Schwartz - BMC Systems Biology, 2018 - Springer
Background 25% of breast cancer patients suffer from aggressive HER2-positive tumours
that are characterised by overexpression of the HER2 protein or by its increased tyrosine …

[PDF][PDF] Degenerative alterations of the cementum–periodontal ligament complex and early tooth loss in a young patient with periodontal disease

SA Petruţiu, P Buiga, A Roman, T Danciu… - Rom J Morphol …, 2012 - academia.edu
Premature exfoliation of primary or permanent teeth in children or adolescents is extremely
rare and it can be a manifestation of an underlying systemic disease. This study aims to …

Hydrolytic and lysozymic degradability of chitosan systems with heparin-mimicking pendant groups

G Tronci, P Buiga, A Alhilou, T Do, SJ Russell… - Materials Letters, 2017 - Elsevier
Chitosan (CT) is an antibacterial polysaccharide that has been investigated for drug carriers,
haemostats and wound dressings. For these applications, customised CT devices can often …

Modelling the role of dual specificity phosphatases in herceptin resistant breast cancer cell lines

P Buiga, A Elson, L Tabernero, JM Schwartz - Computational Biology and …, 2019 - Elsevier
Background Breast cancer remains the most lethal type of cancer for women. A significant
proportion of breast cancer cases are characterised by overexpression of the human …

[PDF][PDF] Clinical and histological characterization of an aggressive periodontitis case associated with unusual root canal curvatures

…, A Roman, P Şurlin, ŞA Petruţiu, P Buiga… - Rom J Morphol …, 2015 - researchgate.net
The article presents the histological and clinical characteristics in a severe generalized
aggressive periodontitis case associated with multiple root curvatures and the complex …

[HTML][HTML] Kinetic modeling of dusp regulation in herceptin-resistant her2-positive breast cancer

P Buiga, A Elson, L Tabernero, JM Schwartz - Genes, 2019 - mdpi.com
Background: HER2 (human epidermal growth factor 2)-positive breast cancer is an aggressive
type of breast cancer characterized by the overexpression of the receptor-type protein …

Opportunities and Challenges Provided by Boolean Modelling of Cancer Signalling Pathways

P Buiga, JM Schwartz - Networks in Systems Biology: Applications for …, 2020 - Springer
Cancer Cancer is a multifactorial disease, which Boolean model involves intricate signalling
pathways Signalling pathway leading to different cellular processes such as survival …

Abstract LB005: Identification of novel targets for MYC-driven hepatocellular carcinoma via transomics

…, SJ Roth, A Singh, C Brown, J Hu, P Buiga… - Cancer Research, 2024 - AACR
Hepatocellular carcinoma (HCC) is an aggressive tumor, and treatment options for patients
with unresectable HCC are limited to targeted therapies and immunotherapy. The activation …