Selective and efficient generation of functional Batf3-dependent CD103+ dendritic cells from mouse bone marrow
CT Mayer, P Ghorbani, A Nandan… - Blood, The Journal …, 2014 - ashpublications.org
Multiple subsets of FMS-like tyrosine kinase 3 ligand (FLT3L)-dependent dendritic cells (DCs)
control T-cell tolerance and immunity. In mice, Batf3-dependent CD103 + DCs efficiently …
control T-cell tolerance and immunity. In mice, Batf3-dependent CD103 + DCs efficiently …
Short-chain fatty acids affect cystic fibrosis airway inflammation and bacterial growth
P Ghorbani, P Santhakumar, Q Hu… - European …, 2015 - Eur Respiratory Soc
… Portions of this manuscript were published as part of the Master's thesis of Peyman
Ghorbani and as an abstract at the European Respiratory Society's annual meeting in 2012 (Vienna, …
Ghorbani and as an abstract at the European Respiratory Society's annual meeting in 2012 (Vienna, …
[HTML][HTML] Choline transport links macrophage phospholipid metabolism and inflammation
SA Snider, KD Margison, P Ghorbani… - Journal of Biological …, 2018 - ASBMB
Choline is an essential nutrient that is required for synthesis of the main eukaryote phospholipid,
phosphatidylcholine. Macrophages are innate immune cells that survey and respond to …
phosphatidylcholine. Macrophages are innate immune cells that survey and respond to …
[HTML][HTML] Interleukin-18 up-regulates amino acid transporters and facilitates amino acid–induced mTORC1 activation in natural killer cells
…, AK Ali, W He, DS Yang, P Ghorbani… - Journal of Biological …, 2019 - ASBMB
Upon inflammation, natural killer (NK) cells undergo metabolic changes to support their high
energy demand for effector function and proliferation. The metabolic changes are usually …
energy demand for effector function and proliferation. The metabolic changes are usually …
[HTML][HTML] A light-driving magnetic nanocomposite based on Zn/Fe/Cu embedded in HKUST-1 applied for adsorption/degradation of Indigo carmine and pathogens
P Ghorbani, ZS Mojtabapour, F Ganjali, FR Asl… - … Technology & Innovation, 2023 - Elsevier
An environmentally friendly photocatalytic system (type-II heterojunction) is designed and
utilized for rapid removal of Indigo carmine (IC) and pathogens from aqueous samples. This …
utilized for rapid removal of Indigo carmine (IC) and pathogens from aqueous samples. This …
Few Foxp3+ regulatory T cells are sufficient to protect adult mice from lethal autoimmunity
CT Mayer, P Ghorbani, AA Kühl, P Stüve… - European journal of …, 2014 - Wiley Online Library
Foxp3 specifies the T reg cell lineage and is indispensable for immune tolerance. Accordingly,
rare Foxp3 mutations cause lethal autoimmunity. The mechanisms precipitating more …
rare Foxp3 mutations cause lethal autoimmunity. The mechanisms precipitating more …
[HTML][HTML] De Novo Fatty Acid Synthesis During Mycobacterial Infection Is a Prerequisite for the Function of Highly Proliferative T Cells, But Not for Dendritic Cells or …
…, M Guderian, F Krull, A Hölscher, P Ghorbani… - Frontiers in …, 2018 - frontiersin.org
Mycobacterium tuberculosis (Mtb), the causative agent of human tuberculosis, is able to
efficiently manipulate the host immune system establishing chronic infection, yet the underlying …
efficiently manipulate the host immune system establishing chronic infection, yet the underlying …
The aryl hydrocarbon receptor in β-cells mediates the effects of TCDD on glucose homeostasis in mice
…, E Poleo-Giordani, AA Hanson, P Ghorbani… - Molecular …, 2024 - Elsevier
Objective Chronic exposure to persistent organic pollutants (POPs) is associated with
increased incidence of type 2 diabetes, hyperglycemia, and poor insulin secretion in humans. …
increased incidence of type 2 diabetes, hyperglycemia, and poor insulin secretion in humans. …
Metabolites: deciphering the molecular language between DCs and their environment
L Minarrieta, P Ghorbani, T Sparwasser… - Seminars in …, 2017 - Springer
Dendritic cells (DCs) determine the outcome of the immune response based on signals they
receive from the environment. Presentation of antigen under various contexts can lead to …
receive from the environment. Presentation of antigen under various contexts can lead to …
[HTML][HTML] Rapid rebound of the Treg compartment in DEREG mice limits the impact of Treg depletion on mycobacterial burden, but prevents autoimmunity
…, J Behrends, M Swallow, F Kruse, F Krull, P Ghorbani… - PLoS …, 2014 - journals.plos.org
The development of an effective vaccine against tuberculosis (Tb) represents one of the
major medical challenges of this century. Mycobacterium bovis Bacille Calmette-Guerin (BCG), …
major medical challenges of this century. Mycobacterium bovis Bacille Calmette-Guerin (BCG), …