Shigellosis is the major global cause of dysentery. Shigella sonnei, which has historically
been more commonly isolated in developed countries, is undergoing an unprecedented …

Shigella spp. are some of the key pathogens responsible for the global burden of diarrhoeal
disease. These facultative intracellular bacteria belong to the family Enterobacteriaceae, …

The emergence of multidrug-resistant (MDR) typhoid is a major global health threat affecting
many countries where the disease is endemic. Here whole-genome sequence analysis of …

Background Shigellosis is an acute, severe bacterial colitis that, in high-income countries, is
typically associated with travel to high-risk regions (Africa, Asia, and Latin America). Since …

Shigella sonnei is a human-adapted pathogen that is emerging globally as the dominant agent
of bacterial dysentery. To investigate local establishment, we sequenced the genomes of …

Typhoid fever, caused by Salmonella enterica serovar Typhi (S. Typhi), remains a serious
global health concern. Since their emergence in the mid-1970s multi-drug resistant (MDR) S. …

10.7554/eLife.14003.001 The interplay between bacterial antimicrobial susceptibility,
phylogenetics and patient outcome is poorly understood. During a typhoid clinical treatment trial in …

10.7554/eLife.07335.001 Shigella flexneri is the most common cause of bacterial dysentery
in low-income countries. Despite this, S. flexneri remains largely unexplored from a genomic …

The use of whole-genome sequencing as a tool for the study of infectious bacteria is of growing
clinical interest. Chlamydia trachomatis is responsible for sexually transmitted infections …

Typhoid is a systemic infection caused by Salmonella Typhi and Salmonella Paratyphi A,
human-restricted bacteria that are transmitted faeco-orally. Salmonella Typhi and S. Paratyphi …