Virtually all mass spectrometric-based methods for quantitative proteomics are at the peptide
level, whether label-mediated or label-free. Absolute quantification in particular is based on …

Phosphorylation is a key regulator of protein function under (patho)physiological conditions,
and defining site‐specific phosphorylation is essential to understand basic and disease …

SARS-CoV-2 is the causative agent behind the COVID-19 pandemic, responsible for over
170 million infections, and over 3.7 million deaths worldwide. Efforts to test, treat and …

In this paper, we discuss the challenge of large‐scale quantification of a proteome, referring
to our programme that aims to define the absolute quantity, in copies per cell, of at least …

The molecular mechanisms underlying skeletal muscle aging and associated sarcopenia
have been linked to an altered oxidative status of redox-sensitive proteins. Reactive oxygen …

How thylakoid membranes are generated to form a metabolically active membrane network
and how thylakoid membranes orchestrate the insertion and localization of protein …

Background Ejaculates contain a diverse mixture of sperm and seminal fluid proteins, the
combination of which is crucial to male reproductive success under competitive conditions. …

Defining intracellular protein concentration is critical in molecular systems biology. Although
strategies for determining relative protein changes are available, defining robust absolute …

Prefractionation of complex mixtures of proteins derived from biological samples is
indispensable for proteome analysis via top-down mass spectrometry (MS). Polyacrylamide gel …

Some enteric bacteria including Salmonella have evolved the propanediol-utilising
microcompartment (Pdu MCP), a specialised proteinaceous organelle that is essential for 1,2-…