[HTML][HTML] Disrupting assembly of the inner membrane complex blocks Plasmodium falciparum sexual stage development

M Parkyn Schneider, B Liu, P Glock, A Suttie… - PLoS …, 2017 - journals.plos.org
Transmission of malaria parasites relies on the formation of a specialized blood form called
the gametocyte. Gametocytes of the human pathogen, Plasmodium falciparum, adopt a …

[HTML][HTML] The MinDE system is a generic spatial cue for membrane protein distribution in vitro

B Ramm, P Glock, J Mücksch, P Blumhardt… - Nature …, 2018 - nature.com
The E. coli MinCDE system has become a paradigmatic reaction–diffusion system in biology.
The membrane-bound ATPase MinD and ATPase-activating protein MinE oscillate …

[HTML][HTML] TransCon IL-2 β/γ: a novel long-acting prodrug with sustained release of an IL-2Rβ/γ-selective IL-2 variant with improved pharmacokinetics and potent …

…, T Kurpiers, M Schnabel, D Reich, P Glock… - … for Immunotherapy of …, 2022 - ncbi.nlm.nih.gov
Background Recombinant interleukin-2 (IL-2, aldesleukin) is an approved cancer immunotherapy
but causes severe toxicities including cytokine storm and vascular leak syndrome (VLS…

Stationary patterns in a two-protein reaction-diffusion system

P Glock, B Ramm, T Heermann, S Kretschmer… - ACS synthetic …, 2018 - ACS Publications
Patterns formed by reaction-diffusion mechanisms are crucial for the development or sustenance
of most organisms in nature. Patterns include dynamic waves, but are more often found …

Design of biochemical pattern forming systems from minimal motifs

P Glock, F Brauns, J Halatek, E Frey, P Schwille - Elife, 2019 - elifesciences.org
Although molecular self-organization and pattern formation are key features of life, only very
few pattern-forming biochemical systems have been identified that can be reconstituted and …

In vitro reconstitution of self-organizing protein patterns on supported lipid bilayers

B Ramm, P Glock, P Schwille - JoVE (Journal of Visualized Experiments), 2018 - jove.com
Many aspects of the fundamental spatiotemporal organization of cells are governed by
reaction-diffusion type systems. In vitro reconstitution of such systems allows for detailed studies …

Optical control of a biological reaction–diffusion system

P Glock, J Broichhagen, S Kretschmer… - Angewandte …, 2018 - Wiley Online Library
Patterns formed by reaction and diffusion are the foundation for many phenomena in biology.
However, the experimental study of reaction–diffusion (R–D) systems has so far been …

Some advice for psychologists who want to work with computer scientists on big data

CJ König, AM Demetriou, P Glock… - Personnel Assessment …, 2020 - repub.eur.nl
This article is based on conversations from the project “Big Data in Psychological Assessment”
(BDPA) funded by the European Union, which was initiated because of the advances in …

Increasing MinD's membrane affinity yields standing wave oscillations and functional gradients on flat membranes

…, T Heermann, A Tassinari, P Glock… - ACS Synthetic …, 2021 - ACS Publications
The formation of large-scale patterns through molecular self-organization is a basic principle
of life. Accordingly, the engineering of protein patterns and gradients is of prime relevance …

On scalable data mining techniques for earth science

…, C Bodenstein, G Cavallaro, P Glock… - Procedia computer …, 2015 - Elsevier
One of the observations made in earth data science is the massive increase of data volume (eg,
higher resolution measurements) and dimensionality (eg hyper-spectral bands). …