Cancer initiation and progression follow complex molecular and structural changes in the
extracellular matrix and cellular architecture of living tissue. However, it remains poorly …

At the stage of carcinoma in situ, the basement membrane (BM) segregates tumor cells from
the stroma. This barrier must be breached to allow dissemination of the tumor cells to …

Basement membranes (BMs) are thin sheets of extracellular matrix that outline epithelia,
muscle fibers, blood vessels and peripheral nerves. The current view of BM structure and …

The current study investigates the structural and compositional changes of ocular basement
membranes (BMs) during long-term diabetes. By comparing retinal vascular BMs and the …

The current basement membrane (BM) model proposes a single-layered extracellular matrix
(ECM) sheet that is predominantly composed of laminins, collagen IVs and proteoglycans. …

Centrosomes are the main microtubule‐organizing centers of animal cells. Although centrosome
aberrations are common in tumors, their consequences remain subject to debate. Here, …

The thymus provides the physiological microenvironment critical for the development of T
lymphocytes, the cells that orchestrate the adaptive immune system to generate an antigen‐…

In vitro cardiac models able to mimic the fibrotic process are paramount to develop an
effective anti-fibrosis therapy that can regulate fibroblast behaviour upon myocardial injury. In …

Purpose: Cataract surgery requires the removal of a circular segment of the anterior lens
capsule (LC) by manual or femtosecond laser (FL) capsulotomy. Tears in the remaining anterior …

The invasive properties of cancer cells are intimately linked to their mechanical phenotype,
which can be regulated by intracellular biochemical signalling. Cell contractility, induced by …