Numerous antibodies that neutralize SARS-CoV-2 have been identified, and these generally
target either the receptor-binding domain (RBD) or the N-terminal domain (NTD) of the viral …

The SARS-CoV-2 spike employs mobile receptor-binding domains (RBDs) to engage the
human ACE2 receptor and to facilitate virus entry, which can occur through low-pH-endosomal …

The classical method of measuring binding constants with affinity-based biosensors involves
testing several analyte concentrations over the same ligand surface and regenerating the …

To explore the reliability of Biacore-based assays, 22 study participants measured the binding
of prostate-specific antigen (PSA) to a monoclonal antibody (mAb). Each participant was …

Desmosomes are intercellular adhesive junctions that impart strength to vertebrate tissues.
Their dense, ordered intercellular attachments are formed by desmogleins (Dsgs) and …

Although structural, biochemical, and genetic studies have provided much insight into the
determinants of specificity and affinity of proteins for RNA, little is currently known about the …

Nectins are immunoglobulin superfamily glycoproteins that mediate intercellular adhesion
in many vertebrate tissues. Homophilic and heterophilic interactions between nectin family …

Antibodies that potently neutralize SARS-CoV-2 target mainly the receptor-binding domain
or the N-terminal domain (NTD). Over a dozen potently neutralizing NTD-directed antibodies …

Alternatively spliced β-neurexins (β-NRXs) and neuroligins (NLs) are thought to have distinct
extracellular binding affinities, potentially providing a β-NRX/NL synaptic recognition code. …

In this benchmark study, 26 investigators were asked to characterize the kinetics and affinities
of 10 sulfonamide inhibitors binding to the enzyme carbonic anhydrase II using Biacore …