A neurotransmitter produced by gut bacteria modulates host sensory behaviour

…, BW Fox, PH Chao, FC Schroeder, P Sengupta - Nature, 2020 - nature.com
Animals coexist in commensal, pathogenic or mutualistic relationships with complex communities
of diverse organisms, including microorganisms 1 . Some bacteria produce bioactive …

[HTML][HTML] odr-10 encodes a seven transmembrane domain olfactory receptor required for responses to the odorant diacetyl

P Sengupta, JH Chou, CI Bargmann - Cell, 1996 - cell.com
Olfactory signaling is initiated by interactions between odorants and olfactory receptors. We
show that the C. elegans odr-10 gene is likely to encode a receptor for the odorant diacetyl. …

The C. elegans gene odr-7 encodes an olfactory-specific member of the nuclear receptor superfamily

P Sengupta, HA Colbert, CI Bargmann - Cell, 1994 - Elsevier
Olfactory discrimination is achieved through the action of olfactory neurons with diverse
chemical specificities. In C. elegans, at least ten different types of chemosensory neurons …

elipsa is an early determinant of ciliogenesis that links the IFT particle to membrane-associated small GTPase Rab8

…, W Kim, T Furukawa, P Sengupta… - Nature cell …, 2008 - nature.com
The formation and function of cilia involves the movement of intraflagellar transport (IFT)
particles underneath the ciliary membrane, along axonemal microtubules 1 , 2 . Although this …

[HTML][HTML] Regulation of body size and behavioral state of C. elegans by sensory perception and the EGL-4 cGMP-dependent protein kinase

M Fujiwara, P Sengupta, SL McIntire - Neuron, 2002 - cell.com
The growth and behavior of higher organisms depend on the accurate perception and
integration of sensory stimuli by the nervous system. We show that defects in sensory perception …

[HTML][HTML] Odorant receptor localization to olfactory cilia is mediated by ODR-4, a novel membrane-associated protein

ND Dwyer, ER Troemel, P Sengupta, CI Bargmann - Cell, 1998 - cell.com
Seven transmembrane domain receptors can be localized to different parts of the plasma
membrane or to different intracellular compartments in a receptor-specific and cell type–…

The AFD sensory neurons encode multiple functions underlying thermotactic behavior in Caenorhabditis elegans

DA Clark, D Biron, P Sengupta… - Journal of …, 2006 - Soc Neuroscience
The thermotactic behaviors of Caenorhabditis elegans indicate that its thermosensory system
exhibits exquisite temperature sensitivity, long-term plasticity, and the ability to transform …

Two Chemoreceptors Mediate Developmental Effects of Dauer Pheromone in C. elegans

…, JR Ragains, J Clardy, K Touhara, P Sengupta - Science, 2009 - science.org
Intraspecific chemical communication is mediated by signals called pheromones. Caenorhabditis
elegans secretes a mixture of small molecules (collectively termed dauer pheromone) …

An ARL3–UNC119–RP2 GTPase cycle targets myristoylated NPHP3 to the primary cilium

…, PR Pretorius, VC Sheffield, P Sengupta… - Genes & …, 2011 - genesdev.cshlp.org
The membrane of the primary cilium is a highly specialized compartment that organizes
proteins to achieve spatially ordered signaling. Disrupting ciliary organization leads to diseases …

Running hot and cold: behavioral strategies, neural circuits, and the molecular machinery for thermotaxis in C. elegans and Drosophila

…, MB Goodman, AD Samuel, P Sengupta - Genes & …, 2010 - genesdev.cshlp.org
Like other ectotherms, the roundworm Caenorhabditis elegans and the fruit fly Drosophila
melanogaster rely on behavioral strategies to stabilize their body temperature. Both animals …