Proteostasis imbalance is emerging as a major hallmark of cancer, driving tumor
aggressiveness. Evidence suggests that the endoplasmic reticulum ( ER ), a major site for protein …

Cellular stress induced by the accumulation of misfolded proteins at the endoplasmic
reticulum (ER) is a central feature of secretory cells and is observed in many tissues in various …

Background The standard of care for newly diagnosed glioblastoma is maximal safe
surgical resection, followed by chemoradiation therapy. We assessed carmustine wafer …

Purpose: CD90 (Thy-1) is a glycophosphatidylinositol-anchored glycoprotein considered as
a surrogate marker for a variety of stem cells, including glioblastoma (GBM) stem cells (GSC)…

We assessed prognostic factors in relation to OS from progression in recurrent glioblastomas.
Retrospective multicentric study enrolling 407 (training set) and 370 (external validation set…

Glioblastoma multiforme (GBM) is the most severe primary brain cancer. Despite an aggressive
treatment comprising surgical resection and radio/chemotherapy, patient's survival post …

Background. Anaplastic gangliogliomas (GGGs) are rare tumors whose natural history is
poorly documented. We aimed to define their clinical and imaging features and to identify …

… Pierre-Jean Le Reste Pierre-Jean Le Reste … David Luque-Paz, Matthieu Revest, François
Eugène, Sarrah Boukthir, Loren Dejoies, Pierre Tattevin, Pierre-Jean Le Reste, Ventriculitis: A …

A growing literature supports maximal safe resection followed by standard combined
chemoradiotherapy (ie maximal first-line therapy) for selected elderly glioblastoma patients. To …

Background To assess the influence of the time interval between surgical resection and
standard combined chemoradiotherapy on survival in newly diagnosed and homogeneously …