Inositol phospholipids have long been known to have an important regulatory role in cell
physiology. The repertoire of cellular processes known to be directly or indirectly controlled by …

Dynamin, a crucial factor in endocytosis 1 , 2 , 3 , is a member of a family of GTPases that
participates in membrane fission 4 , 5 , 6 . It was initially proposed to act as a machine that …

SYNAPTOJANIN is a nerve terminal protein of relative molecular mass 145,000 which
appears to participate with dynamin in synaptic vesicle recycling 1,2 . The central region of …

Growing evidence suggests that phosphoinositides play an important role in membrane
traffic. A polyphosphoinositide phosphatase, synaptojanin 1, was identified as a major …

Amphiphysin, a protein that is highly concentrated in nerve terminals, has been proposed to
function as a linker between the clathrin coat and dynamin in the endocytosis of synaptic …

Phosphorylated products of phosphatidylinositol play critical roles in the regulation of membrane
traffic, in addition to their classical roles as second messengers in signal transduction at …

Protein interactions form a network whose structure drives cellular function and whose
organization informs biological inquiry. Using high-throughput affinity-purification mass …

Dynamin, the founding member of a family of dynamin-like proteins (DLPs) implicated in
membrane remodelling, has a critical role in endocytic membrane fission events. The use of …

The pancreatic islet β-cell autoantigen of relative molecular mass 64,000 (64K), which is a
major target of autoantibodies associated with the development of insulin-dependent diabetes …

… Floyd, Kristin Rose, Pietro De Camilli; Generation of high curvature membranes mediated
by direct endophilin bilayer interactions . J Cell Biol 15 October 2001; 155 (2): 193–200. doi: …