[HTML][HTML] Immunogenicity and reactogenicity of BNT162b2 booster in ChAdOx1-S-primed participants (CombiVacS): a multicentre, open-label, randomised, controlled …
…, MJ Bertran, J García-Pérez, M Campins, A Portolés… - The Lancet, 2021 - thelancet.com
Background To date, no immunological data on COVID-19 heterologous vaccination schedules
in humans have been reported. We assessed the immunogenicity and reactogenicity of …
in humans have been reported. We assessed the immunogenicity and reactogenicity of …
[PDF][PDF] Differential effects of the second SARS-CoV-2 mRNA vaccine dose on T cell immunity in naive and COVID-19 recovered individuals
…, ME Iribarren, J Portoles, MP Rojo-Portoles… - Cell reports, 2021 - cell.com
The rapid development of mRNA-based vaccines against the severe acute respiratory
syndrome coronavirus-2 (SARS-CoV-2) led to the design of accelerated vaccination schedules …
syndrome coronavirus-2 (SARS-CoV-2) led to the design of accelerated vaccination schedules …
Monoclonal antibodies to murine CD3 epsilon define distinct epitopes, one of which may interact with CD4 during T cell activation.
P Portoles, J Rojo, A Golby, M Bonneville… - … (Baltimore, Md.: 1950 …, 1989 - journals.aai.org
The TCR is comprised of two variable chains that confer specificity, called alpha:beta or
gamma:delta, physically associated with five different molecules that comprise the complex …
gamma:delta, physically associated with five different molecules that comprise the complex …
Characterization of H4: a mouse T lymphocyte activation molecule functionally associated with the CD3/T cell receptor
…, U Dianzani, JM Rojo, P Portolés… - European journal of …, 1996 - Wiley Online Library
The monoclonal antibody C398.4A was produced by immunizing Armenian hamsters with
the mouse T cell clone D10.G4.1. It recognizes a molecule selectively expressed by activated …
the mouse T cell clone D10.G4.1. It recognizes a molecule selectively expressed by activated …
[HTML][HTML] Development of potent cellular and humoral immune responses in long-term hemodialysis patients after 1273-mRNA SARS-CoV-2 vaccination
…, P Portoles, A Ortiz, J Portoles… - Frontiers in …, 2022 - frontiersin.org
Long-term hemodialysis (HD) patients are considered vulnerable and at high-risk of developing
severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2) infection due to …
severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2) infection due to …
[HTML][HTML] Maintenance of potent cellular and humoral immune responses in long-term hemodialysis patients after 1273-mRNA SARS-CoV-2 vaccination
…, E Gonzalez-Parra, P Portolés, A Ortiz, J Portoles… - Pharmaceuticals, 2023 - mdpi.com
Continuous evaluation of the coronavirus disease 2019 (COVID-19) vaccine effectiveness in
hemodialysis (HD) patients is critical in this immunocompromised patient group with higher …
hemodialysis (HD) patients is critical in this immunocompromised patient group with higher …
Mechanisms of H4/ICOS costimulation: effects on proximal TCR signals and MAP kinase pathways
…, U Dianzani, P Portoles… - European journal of …, 2003 - Wiley Online Library
H4/ICOS is a costimulatory molecule related to CD28. Its effects on early TCR signals have
been analyzed in mouse CD4 + Th2 cells, expressing H4/ICOS at higher levels than Th1 …
been analyzed in mouse CD4 + Th2 cells, expressing H4/ICOS at higher levels than Th1 …
Differential effects of the second SARS-CoV-2 mRNA vaccine dose on T cell immunity in naïve and COVID-19 recovered individuals
…, M Lopez-Hoyos, ME Iribarren, J Portoles, P Portoles… - Biorxiv, 2021 - biorxiv.org
The rapid development and deployment of mRNA-based vaccines against the severe acute
respiratory syndrome coronavirus-2 (SARS-CoV-2) led to the design of accelerated …
respiratory syndrome coronavirus-2 (SARS-CoV-2) led to the design of accelerated …
[HTML][HTML] An Immunological Approach to the Biocompatibility of Mesoporous SiO2-CaO Nanospheres
…, D Arcos, P Portolés, MT Portolés - International journal of …, 2020 - mdpi.com
Mesoporous bioactive glass nanospheres (NanoMBGs) have high potential for clinical
applications. However, the impact of these nanoparticles on the immune system needs to be …
applications. However, the impact of these nanoparticles on the immune system needs to be …
T-cell receptor
JM Rojo, R Bello, P Portoles - Multichain Immune Recognition Receptor …, 2008 - Springer
The T-cell antigen receptor complex (TCR/CD3) is a cell surface structure that defines the T
lymphocyte lineage, where it fulfills two basic functions, namely antigen recognition and …
lymphocyte lineage, where it fulfills two basic functions, namely antigen recognition and …