Beyond abandonment to next steps: understanding and designing for life after personal informatics tool use
DA Epstein, M Caraway, C Johnston, A Ping… - Proceedings of the …, 2016 - dl.acm.org
Recent research examines how and why people abandon self tracking tools. We extend this
work with new insights drawn from people reflecting on their experiences after they stop …
work with new insights drawn from people reflecting on their experiences after they stop …
Host genes associated with HIV/AIDS: advances in gene discovery
P An, CA Winkler - Trends in genetics, 2010 - cell.com
Twenty-five years after the discovery of HIV as the cause of AIDS there is still no effective
vaccine and no cure for this disease. HIV susceptibility shows a substantial degree of individual …
vaccine and no cure for this disease. HIV susceptibility shows a substantial degree of individual …
Large T antigens of polyomaviruses: amazing molecular machines
P An, MT Sáenz Robles, JM Pipas - Annual review of …, 2012 - annualreviews.org
The large tumor antigen (T antigen) encoded by simian virus 40 is an amazing molecular
machine because it orchestrates viral infection by modulating multiple fundamental viral and …
machine because it orchestrates viral infection by modulating multiple fundamental viral and …
A lived informatics model of personal informatics
Current models of how people use personal informatics systems are largely based in behavior
change goals. They do not adequately characterize the integration of self-tracking into …
change goals. They do not adequately characterize the integration of self-tracking into …
Relaxation of imprinted genes in human cancer
S Rainier, LA Johnson, CJ Dobry, AJ Ping, PE Grundy… - Nature, 1993 - nature.com
GENOMIC imprinting, or parental allele-specific expression of genes, has been demonstrated
at the molecular level in insects and mice 1,2 but not in man. Imprinting as a potential …
at the molecular level in insects and mice 1,2 but not in man. Imprinting as a potential …
New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk
Levels of circulating glucose are tightly regulated. To identify new loci influencing glycemic
traits, we performed meta-analyses of 21 genome-wide association studies informative for …
traits, we performed meta-analyses of 21 genome-wide association studies informative for …
A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance
AK Manning, MF Hivert, RA Scott, JL Grimsby… - Nature …, 2012 - nature.com
Recent genome-wide association studies have described many loci implicated in type 2
diabetes (T2D) pathophysiology and β-cell dysfunction but have contributed little to the …
diabetes (T2D) pathophysiology and β-cell dysfunction but have contributed little to the …
[HTML][HTML] IFITM genes, variants, and their roles in the control and pathogenesis of viral infections
X Zhao, J Li, CA Winkler, P An, JT Guo - Frontiers in Microbiology, 2019 - frontiersin.org
Interferon-induced transmembrane proteins (IFITMs) are a family of small proteins that localize
in the plasma and endolysosomal membranes. IFITMs not only inhibit viral entry into host …
in the plasma and endolysosomal membranes. IFITMs not only inhibit viral entry into host …
APOL1 genetic variants in focal segmental glomerulosclerosis and HIV-associated nephropathy
JB Kopp, GW Nelson, K Sampath… - Journal of the …, 2011 - journals.lww.com
Trypanolytic variants in APOL1, which encodes apolipoprotein L1, associate with kidney
disease in African Americans, but whether APOL1-associated glomerular disease has a distinct …
disease in African Americans, but whether APOL1-associated glomerular disease has a distinct …
Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways
Through genome-wide association meta-analyses of up to 133,010 individuals of European
ancestry without diabetes, including individuals newly genotyped using the Metabochip, we …
ancestry without diabetes, including individuals newly genotyped using the Metabochip, we …