Beyond abandonment to next steps: understanding and designing for life after personal informatics tool use

DA Epstein, M Caraway, C Johnston, A Ping… - Proceedings of the …, 2016 - dl.acm.org
Recent research examines how and why people abandon self tracking tools. We extend this
work with new insights drawn from people reflecting on their experiences after they stop …

Host genes associated with HIV/AIDS: advances in gene discovery

P An, CA Winkler - Trends in genetics, 2010 - cell.com
Twenty-five years after the discovery of HIV as the cause of AIDS there is still no effective
vaccine and no cure for this disease. HIV susceptibility shows a substantial degree of individual …

Large T antigens of polyomaviruses: amazing molecular machines

P An, MT Sáenz Robles, JM Pipas - Annual review of …, 2012 - annualreviews.org
The large tumor antigen (T antigen) encoded by simian virus 40 is an amazing molecular
machine because it orchestrates viral infection by modulating multiple fundamental viral and …

A lived informatics model of personal informatics

DA Epstein, A Ping, J Fogarty, SA Munson - Proceedings of the 2015 …, 2015 - dl.acm.org
Current models of how people use personal informatics systems are largely based in behavior
change goals. They do not adequately characterize the integration of self-tracking into …

Relaxation of imprinted genes in human cancer

S Rainier, LA Johnson, CJ Dobry, AJ Ping, PE Grundy… - Nature, 1993 - nature.com
GENOMIC imprinting, or parental allele-specific expression of genes, has been demonstrated
at the molecular level in insects and mice 1,2 but not in man. Imprinting as a potential …

New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

J Dupuis, C Langenberg, I Prokopenko, R Saxena… - Nature …, 2010 - nature.com
Levels of circulating glucose are tightly regulated. To identify new loci influencing glycemic
traits, we performed meta-analyses of 21 genome-wide association studies informative for …

A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance

AK Manning, MF Hivert, RA Scott, JL Grimsby… - Nature …, 2012 - nature.com
Recent genome-wide association studies have described many loci implicated in type 2
diabetes (T2D) pathophysiology and β-cell dysfunction but have contributed little to the …

[HTML][HTML] IFITM genes, variants, and their roles in the control and pathogenesis of viral infections

X Zhao, J Li, CA Winkler, P An, JT Guo - Frontiers in Microbiology, 2019 - frontiersin.org
Interferon-induced transmembrane proteins (IFITMs) are a family of small proteins that localize
in the plasma and endolysosomal membranes. IFITMs not only inhibit viral entry into host …

APOL1 genetic variants in focal segmental glomerulosclerosis and HIV-associated nephropathy

JB Kopp, GW Nelson, K Sampath… - Journal of the …, 2011 - journals.lww.com
Trypanolytic variants in APOL1, which encodes apolipoprotein L1, associate with kidney
disease in African Americans, but whether APOL1-associated glomerular disease has a distinct …

Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways

RA Scott, V Lagou, RP Welch, E Wheeler… - Nature …, 2012 - nature.com
Through genome-wide association meta-analyses of up to 133,010 individuals of European
ancestry without diabetes, including individuals newly genotyped using the Metabochip, we …