Common brain disorders are associated with heritable patterns of apparent aging of the brain

…, AA Shadrin, OB Smeland, H Soininen, P Sowa… - Nature …, 2019 - nature.com
Common risk factors for psychiatric and other brain disorders are likely to converge on biological
pathways influencing the development and maintenance of brain structure and function …

Cortical thickness and surface area relate to specific symptoms in early relapsing–remitting multiple sclerosis

GO Nygaard, KB Walhovd, P Sowa… - Multiple Sclerosis …, 2015 - journals.sagepub.com
Background: Cortical atrophy is common in early relapsing–remitting multiple sclerosis (RRMS).
Whether this atrophy is caused by changes in cortical thickness or cortical surface area …

[HTML][HTML] Cross-sectional and longitudinal MRI brain scans reveal accelerated brain aging in multiple sclerosis

…, T Kaufmann, GO Nygaard, MK Beyer, P Sowa… - Frontiers in …, 2019 - frontiersin.org
Multiple sclerosis (MS) is an inflammatory disorder of the central nervous system. By combining
longitudinal MRI-based brain morphometry and brain age estimation using machine …

Serum neurofilament light chain concentration predicts disease worsening in multiple sclerosis

…, IS Leikfoss, SD Bos, P Sowa… - Multiple Sclerosis …, 2022 - journals.sagepub.com
Background: Serum neurofilament light (sNfL) chain is a promising biomarker reflecting
neuro-axonal injury in multiple sclerosis (MS). However, the ability of sNfL to predict outcomes in …

Diagnostic performance of cortical lesions and the central vein sign in multiple sclerosis

…, S Ropele, À Rovira, MM Schoonheim, P Sowa… - JAMA …, 2024 - jamanetwork.com
Importance Multiple sclerosis (MS) misdiagnosis remains an important issue in clinical
practice. Objective To quantify the performance of cortical lesions (CLs) and central vein sign (…

[HTML][HTML] A longitudinal study of disability, cognition and gray matter atrophy in early multiple sclerosis patients according to evidence of disease activity

…, EG Celius, SA de Rodez Benavent, P Sowa… - PloS one, 2015 - journals.plos.org
Piotr Sowa has received minor honoraria for lectures from Novartis, Genzyme and Biogen.
Hanne F. Harbo has received an unrestricted research grant from Novartis Norway and …

Prognostic value of single-subject grey matter networks in early multiple sclerosis

…, D Pareto, A Rovira, J Sastre-Garriga, P Sowa… - Brain, 2024 - academic.oup.com
The identification of prognostic markers in early multiple sclerosis (MS) is challenging and
requires reliable measures that robustly predict future disease trajectories. Ideally, such …

[HTML][HTML] The genetic architecture of human brainstem structures and their involvement in common brain disorders

…, E Schwarz, G Selbæk, H Soininen, P Sowa… - Nature …, 2020 - nature.com
Brainstem regions support vital bodily functions, yet their genetic architectures and involvement
in common brain disorders remain understudied. Here, using imaging-genetics data …

Pneumonitis and fibrosis after breast cancer radiotherapy: occurrence and treatment-related predictors

J Karlsen, T Tandstad, P Sowa, Ø Salvesen… - Acta …, 2021 - Taylor & Francis
Background Radiation pneumonitis (RP) and radiation fibrosis (RF) are common side
effects after breast cancer (BC) radiotherapy (RT). However, there is a great variation in the …

Fatigue and cognition: Pupillary responses to problem‐solving in early multiple sclerosis patients

…, HF Harbo, S Tønnesen, P Sowa… - Brain and …, 2017 - Wiley Online Library
Introduction In early multiple sclerosis ( MS ) patients, cognitive changes and fatigue are
frequent and troublesome symptoms, probably related to both structural and functional brain …