User profiles for Pirta Hotulainen
Pirta HotulainenVerified email at helsinki.fi Cited by 5065 |
Actin in dendritic spines: connecting dynamics to function
P Hotulainen, CC Hoogenraad - Journal of Cell Biology, 2010 - rupress.org
Dendritic spines are small actin-rich protrusions from neuronal dendrites that form the
postsynaptic part of most excitatory synapses and are major sites of information processing and …
postsynaptic part of most excitatory synapses and are major sites of information processing and …
Mechanisms of actin stress fibre assembly
…, P Lappalainen, P Hotulainen - Journal of …, 2008 - Wiley Online Library
Stress fibres are contractile acto‐myosin structures found from many types of non‐muscle
cells, where they are involved in adhesion, motility and morphogenesis. Stress fibres typically …
cells, where they are involved in adhesion, motility and morphogenesis. Stress fibres typically …
[HTML][HTML] A look into the future of the COVID-19 pandemic in Europe: an expert consultation
How will the coronavirus disease 2019 (COVID-19) pandemic develop in the coming months
and years? Based on an expert survey, we examine key aspects that are likely to influence …
and years? Based on an expert survey, we examine key aspects that are likely to influence …
Stress fibers are generated by two distinct actin assembly mechanisms in motile cells
P Hotulainen, P Lappalainen - The Journal of cell biology, 2006 - rupress.org
Stress fibers play a central role in adhesion, motility, and morphogenesis of eukaryotic cells,
but the mechanism of how these and other contractile actomyosin structures are generated …
but the mechanism of how these and other contractile actomyosin structures are generated …
Actin-depolymerizing factor and cofilin-1 play overlapping roles in promoting rapid F-actin depolymerization in mammalian nonmuscle cells
P Hotulainen, E Paunola, MK Vartiainen… - Molecular biology of …, 2005 - Am Soc Cell Biol
Actin-depolymerizing factor (ADF)/cofilins are small actin-binding proteins found in all
eukaryotes. In vitro, ADF/cofilins promote actin dynamics by depolymerizing and severing actin …
eukaryotes. In vitro, ADF/cofilins promote actin dynamics by depolymerizing and severing actin …
Defining mechanisms of actin polymerization and depolymerization during dendritic spine morphogenesis
P Hotulainen, O Llano, S Smirnov… - Journal of Cell …, 2009 - rupress.org
Dendritic spines are small protrusions along dendrites where the postsynaptic components
of most excitatory synapses reside in the mature brain. Morphological changes in these actin-…
of most excitatory synapses reside in the mature brain. Morphological changes in these actin-…
[PDF][PDF] A molecular pathway for myosin II recruitment to stress fibers
S Tojkander, G Gateva, G Schevzov, P Hotulainen… - Current Biology, 2011 - cell.com
Background Cell migration and morphogenesis are driven by both protrusive and contractile
actin filament structures. The assembly mechanisms of lamellipodial and filopodial actin …
actin filament structures. The assembly mechanisms of lamellipodial and filopodial actin …
Cyclase-associated protein 1 (CAP1) promotes cofilin-induced actin dynamics in mammalian nonmuscle cells
E Bertling, P Hotulainen, PK Mattila… - Molecular biology of …, 2004 - Am Soc Cell Biol
Cyclase-associated proteins (CAPs) are highly conserved actin monomer binding proteins
present in all eukaryotes. However, the mechanism by which CAPs contribute to actin …
present in all eukaryotes. However, the mechanism by which CAPs contribute to actin …
[HTML][HTML] An action plan for pan-European defence against new SARS-CoV-2 variants
COVID-19 cases are very high across Europe. Current measures are not reducing virus
spread sufficiently, and new severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) …
spread sufficiently, and new severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) …
Contractility-dependent actin dynamics in cardiomyocyte sarcomeres
A Skwarek-Maruszewska, P Hotulainen… - Journal of cell …, 2009 - journals.biologists.com
In contrast to the highly dynamic actin cytoskeleton in non-muscle cells, actin filaments in
muscle sarcomeres are thought to be relatively stable and undergo dynamics only at their ends…
muscle sarcomeres are thought to be relatively stable and undergo dynamics only at their ends…