Patient-specific computer models have been developed representing a variety of aspects of
the cardiovascular system spanning the disciplines of electrophysiology, electromechanics, …

Patient-specific cardiac models are now being used to guide therapies. The increased use
of patient-specific cardiac simulations in clinical care will give rise to the development of …

Simulation of cardiac electrical activity using the bidomain equations can be a massively
computationally demanding problem. This study provides a comprehensive guide to numerical …

Chaste — Cancer, Heart And Soft Tissue Environment — is an open source C++ library for
the computational simulation of mathematical models developed for physiology and biology. …

Providing therapies tailored to each patient is the vision of precision medicine, enabled by
the increasing ability to capture extensive data about individual patients. In this position paper…

Ongoing developments in cardiac modelling have resulted, in particular, in the development
of advanced and increasingly complex computational frameworks for simulating cardiac …

Chaste (‘Cancer, heart and soft-tissue environment’) is a software library and a set of test
suites for computational simulations in the domain of biology. Current functionality has arisen …

Cardiac electrophysiology models have been developed for over 50 years, and now include
detailed descriptions of individual ion currents and sub-cellular calcium handling. It is …

Key points Mathematical and computational models of cardiac physiology have been an
integral component of cardiac electrophysiology since its inception, and are collectively known …

Protecting and promoting public health is the mission of the US Food and Drug Administration
(FDA). FDA's Center for Devices and Radiological Health (CDRH), which regulates …