User profiles for Prasanth Manohar

Prasanth Manohar

Texas A&M University, PDRA at Ry Young Lab, Center for Phage Technology, College …
Verified email at ag.tamu.edu
Cited by 1340

[HTML][HTML] Therapeutic Characterization and Efficacy of Bacteriophage Cocktails Infecting Escherichia coli, Klebsiella pneumoniae, and Enterobacter Species

P Manohar, AJ Tamhankar, CS Lundborg… - Frontiers in …, 2019 - frontiersin.org
Infections due to antibiotic resistant bacteria are increasing globally and this needs immediate
attention. Bacteriophages are considered an effective alternative for the treatment of …

[HTML][HTML] Isolation, characterization and in vivo efficacy of Escherichia phage myPSH1131

P Manohar, AJ Tamhankar, CS Lundborg, N Ramesh - PloS one, 2018 - journals.plos.org
Phage therapy is the use of lytic bacteriophages to cure infections caused by bacteria. The
aim of this study is to isolate and to characterize the bacteriophages against Escherichia coli …

[HTML][HTML] A biological inventory of prophages in A. baumannii genomes reveal distinct distributions in classes, length, and genomic positions

B Loh, J Chen, P Manohar, Y Yu, X Hua… - Frontiers in …, 2020 - frontiersin.org
Acinetobacter baumannii is of major clinical importance as the bacterial pathogen often
causes hospital acquired infections, further complicated by the high prevalence of antibiotic …

[HTML][HTML] Secondary bacterial infections in patients with viral pneumonia

P Manohar, B Loh, R Nachimuthu, X Hua… - Frontiers in …, 2020 - frontiersin.org
Pulmonary diseases of viral origin are often followed by the manifestation of secondary
infections, leading to further clinical complications and negative disease outcomes. Thus, …

Encapsulation and delivery of therapeutic phages

B Loh, VS Gondil, P Manohar, FM Khan… - Applied and …, 2021 - Am Soc Microbiol
Delivery of therapeutic compounds to the site of action is crucial. While many chemical
substances such as beta-lactam antibiotics can reach therapeutic levels in most parts throughout …

[HTML][HTML] Secondary bacterial infections during pulmonary viral disease: phage therapeutics as alternatives to antibiotics?

P Manohar, B Loh, S Athira, R Nachimuthu… - Frontiers in …, 2020 - frontiersin.org
Secondary bacterial infections manifest during or after a viral infection(s) and can lead to
negative outcomes and sometimes fatal clinical complications. Research and development of …

Synergistic Effects of Phage–Antibiotic Combinations against Citrobacter amalonaticus

P Manohar, M Madurantakam Royam… - ACS infectious …, 2022 - ACS Publications
Non-antibiotic alternative treatments to combat the increasing number of infections caused
by multidrug resistant bacteria are urgently needed. In recent years, bacteriophages have …

The distribution of carbapenem-and colistin-resistance in Gram-negative bacteria from the Tamil Nadu region in India

P Manohar, T Shanthini, R Ayyanar… - Journal of medical …, 2017 - microbiologyresearch.org
Purpose. The occurrence of carbapenem- and colistin-resistance among Gram-negative
bacteria is increasing worldwide. The aim of this study was to understand the distribution of …

[HTML][HTML] Improved lyophilization conditions for long-term storage of bacteriophages

P Manohar, N Ramesh - Scientific reports, 2019 - nature.com
Phage therapy is one of the promising alternatives to combat the increasing problem of
antibiotic resistance. Lyophilization is used for the preparation of pharmaceutical products to …

[HTML][HTML] The therapeutic potential of bacteriophages targeting gram-negative bacteria using Galleria mellonella infection model

P Manohar, R Nachimuthu, BS Lopes - BMC microbiology, 2018 - Springer
Background Phage therapy is the therapeutic use of bacteriophages to treat highly drug
resistant bacterial infections. The current surge in bacteriophage therapy is motivated mainly …