The rate of acute kidney injury (AKI) associated with patients hospitalized with Covid-19, and
associated outcomes are not well understood. This study describes the presentation, risk …

Rationale & Objective Outcomes of patients hospitalized with coronavirus disease 2019 (COVID-19)
and acute kidney injury (AKI) are not well understood. The goal of this study was to …

Given the high risk of infection-related mortality, patients with end-stage kidney disease (ESKD)
may be at increased risk with COVID-19. To assess this, we compared outcomes of …

ANG II has been shown to modulate kidney cell growth and contribute to the pathobiology of
glomerulosclerosis. Glomerular visceral epithelial cell (GEC) injury or loss is considered to …

Laboratory data indicate that morphine decreases the number of peritoneal and alveolar
macrophages (Mφ) and compromises their phagocytic capability for immune complexes and …

Development of higher rates of nondiabetic glomerulosclerosis (GS) in African Americans has
been attributed to two coding sequence variants (G1 and G2) in the APOL1 gene. To date, …

ANG II has been demonstrated to play a role in the progression of tubulointerstial injury. We
studied the direct effect of ANG II on apoptosis of cultured rat renal proximal tubular …

FSGS is characterized by segmental scarring of the glomerulus and is a leading cause of
kidney failure. Identification of genes causing FSGS has improved our understanding of …

… After the cells were washed with PBS, they were permeabilized with 2 mL of 0.01% (vol:vol)
Triton X-100 in PBS buffer for five minutes at 10C and stained with anti-human LC antibody …

Podocytes are an integral and important constituent of the glomerular filtration barrier (GFB)
and are exposed to a higher concentrations of ANG II in diseased states; consequently, …