Genetic susceptibility to dyslipidaemia remains incompletely understood. The liver X receptors
(LXRs), members of the nuclear receptor superfamily of ligand dependent transcription …

Triple negative breast cancer (TNBC) is challenging to treat successfully because targeted
therapies do not exist. Instead, systemic therapy is typically restricted to cytotoxic …

Low fruit and vegetable consumption and high saturated fat consumption causes elevated
circulating cholesterol and are breast cancer risk factors. During cholesterol metabolism, …

The present pharmacotherapy for eosinophilic esophagitis (EoE) fundamentally depend on
inhaled corticosteroids. Despite the fact that oral intake of topical steroids can be successful …

Interventions that alter cholesterol have differential impacts on hormone receptor positive- and
negative-breast cancer risk and prognosis. This implies differential regulation or response …

Activity of liver x receptor (LXR), the homeostatic regulator of cholesterol metabolism, is
elevated in triple-negative breast cancer (BCa) relative to other BCa subtypes, driving drug …

Eosinophilic esophagitis (EoE) is a recently recognized esophageal inflammatory disease
with clinical manifestations arising from esophageal dysfunction. The etiology of EoE is …

Background Quail egg (QE) has been reported to possess an anti-allergic and anti-inflammatory
activity. We have demonstrated that whole QE was able to attenuate the allergic …

The liver x receptors (LXR) alpha and beta are ligand-responsive transcription factors that
link homeostatic control of lipid metabolism with cancer pathophysiology and prognosis. LXR …

Breast cancer treatment and prognosis is informed by biomarker expression. Expression of
Oestrogen Receptor-alpha (ERα) for example influences whether the patient receives …