Spatial transcriptomics (ST) technologies generate multiple data types from biological
samples, namely gene expression, physical distance between data points, and/or tissue …

Simple Summary Ovarian cancer is one of the most lethal cancers affecting women worldwide.
Its high mortality rate is often attributed to the non-specific nature of early symptoms of the …

Background Gestational diabetes mellitus (GDM) is a serious public health issue affecting 9–15%
of all pregnancies worldwide. Recently, it has been suggested that extracellular …

Ovarian cancer (OC) is one of the most diagnosed gynecological cancers in women. Due to
the lack of effective early stage screening, women are more often diagnosed at an advanced …

Purpose: Lacking effective targeted therapies, triple-negative breast cancer (TNBCs) is
highly aggressive and metastatic disease, and remains clinically challenging breast cancer …

Aims A better understanding of the expression of cancer/testis antigens ( CTA s) in breast
cancer might enable the identification of new immunotherapy options, especially for triple‐…

Intratumoral heterogeneity is caused by genomic instability and phenotypic plasticity, but
how these features co-evolve remains unclear. SOX10 is a neural crest stem cell (NCSC) …

During the last decade, the genomics revolution has driven critical advances in molecular
oncology and pathology, and a deeper appreciation of heterogeneity that is beginning to …

Invasive lobular carcinoma (ILC) is the most common special type of breast cancer, and is
characterized by functional loss of E-cadherin, resulting in cellular adhesion defects. ILC …

Brain metastases are the most prevalent of intracranial malignancies. They are associated
with a very poor prognosis and near 100% mortality. This has been the case for decades, …