Sensitive detection of minimal residual disease in patients treated for early-stage breast cancer

…, J Rhoades, SC Reed, G Gydush, P Ram… - Clinical Cancer …, 2020 - AACR
Purpose: Existing cell-free DNA (cfDNA) methods lack the sensitivity needed for detecting
minimal residual disease (MRD) following therapy. We developed a test for tracking hundreds …

A Mucin 16 bispecific T cell–engaging antibody for the treatment of ovarian cancer

…, MP Kelly, K Vazzana, L Canova, P Ram… - Science translational …, 2019 - science.org
Advanced ovarian cancer is frequently treated with combination chemotherapy, but high
recurrence rates show the need for therapies that can produce durable responses and extend …

[HTML][HTML] Generation of T-cell-redirecting bispecific antibodies with differentiated profiles of cytokine release and biodistribution by CD3 affinity tuning

…, S Rizvi, E Damko, D Chiu, K Vazzana, P Ram… - Scientific Reports, 2021 - nature.com
T-cell-redirecting bispecific antibodies have emerged as a new class of therapeutic agents
designed to simultaneously bind to T cells via CD3 and to tumor cells via tumor-cell-specific …

A class of costimulatory CD28-bispecific antibodies that enhance the antitumor activity of CD3-bispecific antibodies

…, A Pawashe, L Canova, K Vazzana, P Ram… - Science translational …, 2020 - science.org
T cell activation is initiated upon binding of the T cell receptor (TCR)/CD3 complex to peptide–major
histocompatibility complexes (“signal 1”); activation is enhanced by engagement of …

[HTML][HTML] Potassium channel-driven bioelectric signalling regulates metastasis in triple-negative breast cancer

SL Payne, P Ram, DH Srinivasan, TT Le, M Levin… - …, 2022 - thelancet.com
Background There is a critical need to better understand the mechanisms that drive local
cell invasion and metastasis to develop new therapeutics targeting metastatic disease. …

A PSMA-targeting CD3 bispecific antibody induces antitumor responses that are enhanced by 4-1BB costimulation

…, R Tavaré, L Haber, OH Aina, K Vazzana, P Ram… - Cancer Immunology …, 2020 - AACR
Priyanka Ram; Priyanka RamRam is a full-time employee at Regeneron
Pharmaceuticals. M. Danton is a full-time employee at Regeneron Pharmaceuticals. …

Identification and agro-morphological characterization of rice genotypes resistant to sheath blight

…, GS Laha, C Priyanka, A Rajkumar, T Ram - Australasian Plant …, 2016 - Springer
Rice is the most widely consumed staple food for a large part of the world’s human population,
especially in Asia. Sheath blight caused by Rhizoctonia solani, is one of the most serious …

Some Kaluza-Klein cosmological models in f(R,T) gravity theory

S Ram, Priyanka - Astrophysics and Space Science, 2013 - Springer
Algorithms are derived for constructing five dimensional Kaluza-Klein cosmological space-times
in the presence of a perfect fluid source in the framework of f(R,T) gravity theory …

Metal pollution index and daily dietary intake of metals through consumption of vegetables

…, Priyanka, V Shukla, S Kumar, RB Ram… - International journal of …, 2020 - Springer
Present study was conducted with an objective to study the concentration of heavy metals,
metal pollution index and daily intake of metal in eight selected vegetables viz. R. sativus (…

Performance Analysis of Distribution System with Optimal Allocation of Unified Power Quality Conditioner Considering Distribution Network Reconfiguration.

Y Priyanka, R Ram - International Journal of Intelligent …, 2023 - search.ebscohost.com
The distribution systems act as the primary connecting point between the power utility and
the end users of the electricity. It is vital to assess the behaviour of the network when …