Rapid antimicrobial susceptibility testing (AST) is urgently needed for treating infections with
appropriate antibiotics and slowing down the emergence of antibiotic‐resistant bacteria. …

Saccharibacteria are a group of widespread and genetically diverse ultrasmall bacteria with
highly reduced genomes that belong to the Candidate Phyla Radiation. Comparative …

Confronted with the severe situation that the pace of resistance acquisition is faster than the
clinical introduction of new antibiotics, health organizations are calling for effective …

Excited state dynamics provides an intrinsic molecular contrast of samples examined. These
dynamics can be monitored by pump probe spectroscopy which measures the change in …

Ergosterol-targeting amphotericin B (AmB) is the first line of defense for life-threatening
fungal infections. Two models have been proposed to illustrate AmB assembly in the cell …

Confronted with the rapid evolution and dissemination of antibiotic resistance, there is an
urgent need to develop alternative treatment strategies for drug‐resistant pathogens. Here, an …

High‐sensitivity chemical imaging offers a window to decipher the molecular orchestra inside
a living system. Based on vibrational fingerprint signatures, coherent Raman scattering …

Bacteria have evolved to cope with the detrimental effects of ROS using their essential
molecular components. Catalase, a heme-containing tetramer protein expressed universally in …

Microbes have developed their own specific strategies to cope with reactive oxygen species
(ROS). Catalase, a heme‐containing tetramer expressed in a broad range of aerobic fungi, …

Candida albicans (C. albicans), a major fungal pathogen, causes life-threatening infections
in immunocompromised individuals. Fluconazole (FLC) is recommended as first-line therapy …