Eradication of gastric cancer is now both possible and practical
A Shiotani, P Cen, DY Graham - Seminars in cancer biology, 2013 - Elsevier
In 1994, Helicobacter pylori was declared a human carcinogen. Evidence has now
accumulated to show that at least 95% of gastric cancers are etiologically related to H. pylori. An …
accumulated to show that at least 95% of gastric cancers are etiologically related to H. pylori. An …
Circulating tumor cells in the diagnosis and management of pancreatic cancer
Pancreatic cancers are typically resistant to chemo and radiation therapy and are predisposed
to distant metastases. Circulating tumor cells (CTCs) are tumor cells disseminated from …
to distant metastases. Circulating tumor cells (CTCs) are tumor cells disseminated from …
A preoperative serum signature of CEA+/CA125+/CA19‐9 ≥ 1000 U/mL indicates poor outcome to pancreatectomy for pancreatic cancer
Pancreatectomy is associated with significant morbidity and unpredictable outcome, with
few diagnostic tools to determine, which patients gain the most benefit from this treatment, …
few diagnostic tools to determine, which patients gain the most benefit from this treatment, …
[HTML][HTML] A phase II, multicenter, single-arm study of mipsagargin (G-202) as a second-line therapy following sorafenib for adult patients with progressive advanced …
D Mahalingam, J Peguero, P Cen, SP Arora… - Cancers, 2019 - mdpi.com
Background: Mipsagargin (G-202) is a thapsigargin-based prodrug with cytotoxic activity
masked by a peptide that is cleaved by prostate-specific membrane antigen (PSMA), a protease …
masked by a peptide that is cleaved by prostate-specific membrane antigen (PSMA), a protease …
[HTML][HTML] The role of CD44 in the pathogenesis, diagnosis, and therapy of gastric cancer
BI Jang, Y Li, DY Graham, P Cen - Gut and liver, 2011 - ncbi.nlm.nih.gov
CD44 is a transmembrane glycoprotein and surface receptor for hyaluronan that is involved
in the response of cells to their microenvironment. CD44 splice variants play roles in …
in the response of cells to their microenvironment. CD44 splice variants play roles in …
[HTML][HTML] Endoscopic ultrasound-guided radiofrequency ablation (EUS-RFA) for advanced pancreatic and periampullary adenocarcinoma
N Thosani, P Cen, J Rowe, S Guha… - Scientific Reports, 2022 - nature.com
Long term prognosis and 5-year survival for pancreatic adenocarcinoma (PDAC) remains
suboptimal. Endoscopic ultrasound (EUS) guided RFA (EUS-RFA) is an emerging technology …
suboptimal. Endoscopic ultrasound (EUS) guided RFA (EUS-RFA) is an emerging technology …
Radiofrequency ablation remodels the tumor microenvironment and promotes neutrophil-mediated abscopal immunomodulation in pancreatic cancer
…, BK Osborn, V Mota, J Chaney, CL Atkins, P Cen… - Cancer immunology …, 2023 - AACR
… All animal procedures were performed in compliance with UTHealth's Center for Laboratory
… with the role of CXCL13 in the activation of the germinal center and adaptive immunity (11). …
… with the role of CXCL13 in the activation of the germinal center and adaptive immunity (11). …
Lymphovascular invasion as a tool to further subclassify T1b esophageal adenocarcinoma
P Cen, WL Hofstetter, AM Correa, TT Wu… - … Journal of the …, 2008 - Wiley Online Library
BACKGROUND. Lymphovascular invasion (LVI) and/or lymph node metastases (LNM)
adversely influence the overall survival (OS) of patients with T1 esophageal adenocarcinoma. …
adversely influence the overall survival (OS) of patients with T1 esophageal adenocarcinoma. …
TroVax in colorectal cancer
J Rowe, P Cen - Human vaccines & immunotherapeutics, 2014 - Taylor & Francis
Currently, the backbone of therapy for metastatic disease is cytotoxic chemotherapy, along
with the recent addition of targeted therapy based on molecular markers with KRAS testing. …
with the recent addition of targeted therapy based on molecular markers with KRAS testing. …
Changes in age, stage distribution, and survival of patients with esophageal adenocarcinoma over three decades in the United States
P Cen, F Banki, L Cheng, K Khalil, XL Du… - Annals of surgical …, 2012 - Springer
Background Our aim was to evaluate the changes in age, stage distribution, and overall
survival (OS) of patients with esophageal adenocarcinoma (EAC) over time. Methods Patients …
survival (OS) of patients with esophageal adenocarcinoma (EAC) over time. Methods Patients …