[HTML][HTML] Mesenchymal stem cells and immunomodulation: current status and future prospects
The unique immunomodulatory properties of mesenchymal stem cells (MSCs) make them
an invaluable cell type for the repair of tissue/organ damage caused by chronic inflammation …
an invaluable cell type for the repair of tissue/organ damage caused by chronic inflammation …
Paracrine mechanisms of mesenchymal stem cell-based therapy: current status and perspectives
… ), National Natural Science Grant of China (81170896), and small project funding from
The University of Hong Kong (201111159183 to Q. Lian). The authors declare no conflicts of …
The University of Hong Kong (201111159183 to Q. Lian). The authors declare no conflicts of …
[HTML][HTML] Mesenchymal stem cell-derived extracellular vesicles for immunomodulation and regeneration: a next generation therapeutic tool?
Mesenchymal stem cells (MSCs) can be widely isolated from various tissues including bone
marrow, umbilical cord, and adipose tissue, with the potential for self-renewal and …
marrow, umbilical cord, and adipose tissue, with the potential for self-renewal and …
Functional mesenchymal stem cells derived from human induced pluripotent stem cells attenuate limb ischemia in mice
Background— Aging and aging-related disorders impair the survival and differentiation
potential of bone marrow mesenchymal stem cells (MSCs) and limit their therapeutic efficacy. …
potential of bone marrow mesenchymal stem cells (MSCs) and limit their therapeutic efficacy. …
Effect of regional vs general anesthesia on incidence of postoperative delirium in older patients undergoing hip fracture surgery: the RAGA randomized trial
…, S Jin, Y Yao, J Wu, J Chen, FG Smith, Q Lian… - Jama, 2022 - jamanetwork.com
Importance In adults undergoing hip fracture surgery, regional anesthesia may reduce
postoperative delirium, but there is uncertainty about its effectiveness. Objective To investigate, in …
postoperative delirium, but there is uncertainty about its effectiveness. Objective To investigate, in …
[PDF][PDF] A human iPSC model of Hutchinson Gilford Progeria reveals vascular smooth muscle and mesenchymal stem cell defects
J Zhang, Q Lian, G Zhu, F Zhou, L Sui, C Tan… - Cell stem cell, 2011 - cell.com
The segmental premature aging disease Hutchinson-Gilford Progeria syndrome (HGPS) is
caused by a truncated and farnesylated form of Lamin A called progerin. HGPS affects …
caused by a truncated and farnesylated form of Lamin A called progerin. HGPS affects …
[HTML][HTML] Recurrently deregulated lncRNAs in hepatocellular carcinoma
Hepatocellular carcinoma (HCC) cells often invade the portal venous system and
subsequently develop into portal vein tumour thrombosis (PVTT). Long noncoding RNAs (lncRNAs) …
subsequently develop into portal vein tumour thrombosis (PVTT). Long noncoding RNAs (lncRNAs) …
Derivation of clinically compliant MSCs from CD105+, CD24− differentiated human ESCs
Q Lian, E Lye, K Suan Yeo, E Khia Way Tan… - Stem …, 2007 - academic.oup.com
Adult tissue-derived mesenchymal stem cells (MSCs) have demonstrated therapeutic
efficacy in treating diseases or repairing damaged tissues through mechanisms thought to be …
efficacy in treating diseases or repairing damaged tissues through mechanisms thought to be …
Comprehensive analysis of spatial architecture in primary liver cancer
Heterogeneity is the major challenge for cancer prevention and therapy. Here, we first
constructed high-resolution spatial transcriptomes of primary liver cancers (PLCs) containing …
constructed high-resolution spatial transcriptomes of primary liver cancers (PLCs) containing …
Human pluripotent stem cell-derived mesenchymal stem cells prevent allergic airway inflammation in mice
… We also demonstrated a difference in the secretome profiles between iPSC-MSCs and
BM-MSCs against anthracclines-induced cardiomyopathy (Q. Lian et al., manuscript submitted for …
BM-MSCs against anthracclines-induced cardiomyopathy (Q. Lian et al., manuscript submitted for …