User profiles for Q. Marcou
Quentin MARCOUPhD, Public Health resident Aix-Marseille Université Verified email at etu.univ-amu.fr Cited by 674 |
[HTML][HTML] High-throughput immune repertoire analysis with IGoR
High-throughput immune repertoire sequencing is promising to lead to new statistical diagnostic
tools for medicine and biology. Successful implementations of these methods require a …
tools for medicine and biology. Successful implementations of these methods require a …
Inferring processes underlying B-cell repertoire diversity
… Using the (hypermutation-free) generation model as a starting point, we infer selection factors
Q acting on each sequence in the naive repertoire, where Q is defined as the fold increase …
Q acting on each sequence in the naive repertoire, where Q is defined as the fold increase …
[HTML][HTML] Persisting fetal clonotypes influence the structure and overlap of adult human T cell receptor repertoires
… in-frame sequences and calculated the Q selection factors for each … in-frame datasets was
reweighted by the Q factors as: (1) … sequences of the two individuals, and Q (1) (s), Q (2) (s) are …
reweighted by the Q factors as: (1) … sequences of the two individuals, and Q (1) (s), Q (2) (s) are …
[HTML][HTML] Genesis of the αβ T-cell receptor
… was kept with probability q to mimick thymic selection [17]. … , so that the ratio q is given by
q α q β , where q α,β are the … value of q is inferred by least-square minimisation to be q α = …
q α q β , where q α,β are the … value of q is inferred by least-square minimisation to be q α = …
repgenHMM: a dynamic programming tool to infer the rules of immune receptor generation from sequence data
Motivation: The diversity of the immune repertoire is initially generated by random
rearrangements of the receptor gene during early T and B cell development. Rearrangement …
rearrangements of the receptor gene during early T and B cell development. Rearrangement …
How different are self and nonself?
Biological and artificial neural networks routinely make reliable distinctions between similar
inputs, and the rules for making these distinctions are learned. In some ways, self/nonself …
inputs, and the rules for making these distinctions are learned. In some ways, self/nonself …
Quantifying physician's bias to terminate resuscitation. The TERMINATOR study
T Laurenceau, Q Marcou, JM Agostinucci, L Martineau… - Resuscitation, 2023 - Elsevier
Context Deciding on “termination of resuscitation” (TOR) is a dilemma for any physician
facing cardiac arrest. Due to the lack of evidence-based criteria and scarcity of the existing …
facing cardiac arrest. Due to the lack of evidence-based criteria and scarcity of the existing …
[HTML][HTML] Creating a computer assisted ICD coding system: performance metric choice and use of the ICD hierarchy
Q Marcou, L Berti-Equille, N Novelli - Journal of Biomedical Informatics, 2024 - Elsevier
Objective: Machine learning methods hold the promise of leveraging available data and
generating higher-quality data while alleviating the data collection burden on healthcare …
generating higher-quality data while alleviating the data collection burden on healthcare …
IGoR: a tool for high-throughput immune repertoire analysis
… This inequality ensures that maximizing the “pseudo-log-likelihood” Q(θ |θ) over θ increases
total likelihood by at least the same amount. The Expectation-Maximization scheme updates …
total likelihood by at least the same amount. The Expectation-Maximization scheme updates …
Financeirização e transformações recentes no circuito imobiliário no Brasil
M Fix - 2011 - repositorio.unicamp.br
… Resumo: A onda de despejos que marcou a crise financeira … Resumo: A onda de despejos
que marcou a crise financeira … fictício nesse período, o que, combinado a formas antigas de …
que marcou a crise financeira … fictício nesse período, o que, combinado a formas antigas de …