User profiles for Q. Marcou

Quentin MARCOU

PhD, Public Health resident Aix-Marseille Université
Verified email at etu.univ-amu.fr
Cited by 674

[HTML][HTML] High-throughput immune repertoire analysis with IGoR

Q Marcou, T Mora, AM Walczak - Nature communications, 2018 - nature.com
High-throughput immune repertoire sequencing is promising to lead to new statistical diagnostic
tools for medicine and biology. Successful implementations of these methods require a …

Inferring processes underlying B-cell repertoire diversity

Y Elhanati, Z Sethna, Q Marcou… - … of the Royal …, 2015 - royalsocietypublishing.org
… Using the (hypermutation-free) generation model as a starting point, we infer selection factors
Q acting on each sequence in the naive repertoire, where Q is defined as the fold increase …

[HTML][HTML] Persisting fetal clonotypes influence the structure and overlap of adult human T cell receptor repertoires

MV Pogorelyy, Y Elhanati, Q Marcou… - PLoS computational …, 2017 - journals.plos.org
… in-frame sequences and calculated the Q selection factors for each … in-frame datasets was
reweighted by the Q factors as: (1) … sequences of the two individuals, and Q (1) (s), Q (2) (s) are …

[HTML][HTML] Genesis of the αβ T-cell receptor

T Dupic, Q Marcou, AM Walczak… - PLoS computational …, 2019 - journals.plos.org
… was kept with probability q to mimick thymic selection [17]. … , so that the ratio q is given by
q α q β , where q α,β are the … value of q is inferred by least-square minimisation to be q α = …

repgenHMM: a dynamic programming tool to infer the rules of immune receptor generation from sequence data

Y Elhanati, Q Marcou, T Mora, AM Walczak - Bioinformatics, 2016 - academic.oup.com
Motivation: The diversity of the immune repertoire is initially generated by random
rearrangements of the receptor gene during early T and B cell development. Rearrangement …

How different are self and nonself?

A Mayer, CJ Russo, Q Marcou, W Bialek… - arXiv preprint arXiv …, 2022 - arxiv.org
Biological and artificial neural networks routinely make reliable distinctions between similar
inputs, and the rules for making these distinctions are learned. In some ways, self/nonself …

Quantifying physician's bias to terminate resuscitation. The TERMINATOR study

T Laurenceau, Q Marcou, JM Agostinucci, L Martineau… - Resuscitation, 2023 - Elsevier
Context Deciding on “termination of resuscitation” (TOR) is a dilemma for any physician
facing cardiac arrest. Due to the lack of evidence-based criteria and scarcity of the existing …

[HTML][HTML] Creating a computer assisted ICD coding system: performance metric choice and use of the ICD hierarchy

Q Marcou, L Berti-Equille, N Novelli - Journal of Biomedical Informatics, 2024 - Elsevier
Objective: Machine learning methods hold the promise of leveraging available data and
generating higher-quality data while alleviating the data collection burden on healthcare …

IGoR: a tool for high-throughput immune repertoire analysis

Q Marcou, T Mora, AM Walczak - arXiv preprint arXiv:1705.08246, 2017 - arxiv.org
… This inequality ensures that maximizing the “pseudo-log-likelihood” Q(θ |θ) over θ increases
total likelihood by at least the same amount. The Expectation-Maximization scheme updates …

Financeirização e transformações recentes no circuito imobiliário no Brasil

M Fix - 2011 - repositorio.unicamp.br
… Resumo: A onda de despejos que marcou a crise financeira … Resumo: A onda de despejos
que marcou a crise financeira … fictício nesse período, o que, combinado a formas antigas de …