Background: Studies have suggested that the fat mass and obesity–associated (FTO)
genotype is associated with individual variability in weight loss in response to diet/lifestyle …

To study the effect of host genetics on gut microbiome composition, the MiBioGen consortium
curated and analyzed genome-wide genotypes and 16S fecal microbiome data from …

Background Temporal increases in the consumption of sugar-sweetened beverages have
paralleled the rise in obesity prevalence, but whether the intake of such beverages interacts …

The gut microbiome is an important contributor to human health, shaped by many endogenous
and exogenous factors. The gut microbiome displays sexual dimorphism, suggesting …

Importance The 2015-2020 Dietary Guidelines for Americans recommend multiple healthy
eating patterns. However, few studies have examined the associations of adherence to …

Objective To examine the interactions between genetic predisposition and consumption of
fried food in relation to body mass index (BMI) and obesity. Design Prospective cohort study. …

To increase our understanding of the genetic basis of adiposity and its links to cardiometabolic
disease risk, we conducted a genome-wide association meta-analysis of body fat …

Objective Tryptophan can be catabolised to various metabolites through host kynurenine
and microbial indole pathways. We aimed to examine relationships of host and microbial …

Although more than 20 genetic susceptibility loci have been reported for type 2 diabetes (T2D),
most reported variants have small to moderate effects and account for only a small …

Context: High retinol-binding protein 4 (RBP4) is thought to be associated with insulin
resistance in humans. However, evidence from large-scale populations about the relationship …