It has been reported that ACE2 is the main host cell receptor of 2019-nCoV and plays a
crucial role in the entry of virus into the cell to cause the final infection. To investigate the …

Tumor progression and the efficacy of immunotherapy are strongly influenced by the composition
and abundance of immune cells in the tumor microenvironment. Due to the limitations …

Osteoarthritis is a highly prevalent and debilitating joint disorder. There is no effective medical
therapy for the condition because of limited understanding of its pathogenesis. We show …

Recent clinical successes of cancer immunotherapy necessitate the investigation of the
interaction between malignant cells and the host immune system. However, elucidation of …

Receptor for activated C kinase 1 (RACK1) has been shown to promote oral squamous cell
carcinoma (OSCC) progression, and RACK1 expression levels have been negatively …

We developed a computational method to infer the complementarity-determining region 3 (CDR3)
sequences of tumor-infiltrating T cells in 9,142 RNA-seq samples across 29 cancer …

Smart hydrogels, or stimuli-responsive hydrogels, are three-dimensional networks composed
of crosslinked hydrophilic polymer chains that are able to dramatically change their volume …

Mutually exclusive activating mutations in the GNAQ and GNA11 oncogenes, encoding
heterotrimeric Gαq family members, have been identified in ∼83% and ∼6% of uveal and skin …

Ionizing radiation-induced DNA damages cause genome instability and are highly cytotoxic.
Deoxyribonucleotide metabolism provides building blocks for DNA repair. Nevertheless, …

Periodontitis is an inflammatory disease involving the destruction of both soft and hard tissue
in the periodontal region. Although dysbiosis of the local microbial community initiates local …