User profiles for Qiaonan Duan
 | Qiaonan DuanNuMedii, Inc. Verified email at icahn.mssm.edu Cited by 17267 |
Enrichr: a comprehensive gene set enrichment analysis web server 2016 update
…, AD Rouillard, NF Fernandez, Q Duan… - Nucleic acids …, 2016 - academic.oup.com
Enrichment analysis is a popular method for analyzing gene sets generated by genome-wide
experiments. Here we present a significant update to one of the tools in this domain called …
experiments. Here we present a significant update to one of the tools in this domain called …
Single-cell RNA-seq reveals ectopic and aberrant lung-resident cell populations in idiopathic pulmonary fibrosis
We provide a single-cell atlas of idiopathic pulmonary fibrosis (IPF), a fatal interstitial lung
disease, by profiling 312,928 cells from 32 IPF, 28 smoker and nonsmoker controls, and 18 …
disease, by profiling 312,928 cells from 32 IPF, 28 smoker and nonsmoker controls, and 18 …
[HTML][HTML] Enrichr: interactive and collaborative HTML5 gene list enrichment analysis tool
Background System-wide profiling of genes and proteins in mammalian cells produce lists
of differentially expressed genes/proteins that need to be further analyzed for their collective …
of differentially expressed genes/proteins that need to be further analyzed for their collective …
Lean Big Data integration in systems biology and systems pharmacology
Data sets from recent large-scale projects can be integrated into one unified puzzle that can
provide new insights into how drugs and genetic perturbations applied to human cells are …
provide new insights into how drugs and genetic perturbations applied to human cells are …
[PDF][PDF] Minimal differentiation of classical monocytes as they survey steady-state tissues and transport antigen to lymph nodes
It is thought that monocytes rapidly differentiate to macrophages or dendritic cells (DCs) upon
leaving blood. Here we have shown that Ly-6C + monocytes constitutively trafficked into …
leaving blood. Here we have shown that Ly-6C + monocytes constitutively trafficked into …
LINCS Canvas Browser: interactive web app to query, browse and interrogate LINCS L1000 gene expression signatures
For the Library of Integrated Network-based Cellular Signatures (LINCS) project many gene
expression signatures using the L1000 technology have been produced. The L1000 …
expression signatures using the L1000 technology have been produced. The L1000 …
[HTML][HTML] L1000CDS2: LINCS L1000 characteristic direction signatures search engine
The library of integrated network-based cellular signatures (LINCS) L1000 data set currently
comprises of over a million gene expression profiles of chemically perturbed human cell …
comprises of over a million gene expression profiles of chemically perturbed human cell …
[HTML][HTML] Extraction and analysis of signatures from the Gene Expression Omnibus by the crowd
…, AS Feldmann, KS Hu, MG McDermott, Q Duan… - Nature …, 2016 - nature.com
Gene expression data are accumulating exponentially in public repositories. Reanalysis and
integration of themed collections from these studies may provide new insights, but requires …
integration of themed collections from these studies may provide new insights, but requires …
[HTML][HTML] The characteristic direction: a geometrical approach to identify differentially expressed genes
Background Identifying differentially expressed genes (DEG) is a fundamental step in studies
that perform genome wide expression profiling. Typically, DEG are identified by univariate …
that perform genome wide expression profiling. Typically, DEG are identified by univariate …
[HTML][HTML] Activation of tumor suppressor protein PP2A inhibits KRAS-driven tumor growth
…, RC Sears, EY Chen, Q Duan… - The Journal of …, 2017 - Am Soc Clin Investig
Targeted cancer therapies, which act on specific cancer-associated molecular targets, are
predominantly inhibitors of oncogenic kinases. While these drugs have achieved some …
predominantly inhibitors of oncogenic kinases. While these drugs have achieved some …