The T-cell surface molecule TIGIT is an immune checkpoint molecule that inhibits T-cell
responses, but its roles in cancer are little understood. In this study, we evaluated the role TIGIT …

Background & Aims The association between cellular senescence and Helicobacter pylori–induced
atrophic gastritis is not clear. Here, we explore the role of cellular senescence in H …

Prostate cancer (PCa) is the second leading cause of cancer death in American men.
Androgen receptor (AR) signaling is essential for PCa cell growth/survival and remains a key …

About 15–20% of breast cancer (BCa) is triple-negative BCa (TNBC), a devastating disease
with limited therapeutic options. Aberrations in the PI3K/PTEN signaling pathway are …

Mitogen-activated protein kinase 6 (MAPK6) is an atypical MAPK. Its function in regulating
cancer growth remains elusive. Here, we reported that MAPK6 directly activated AKT and …

The characteristics of tropical cyclone (TC) extreme rainfall events over Hainan Island from
1969 to 2014 are analyzed from the viewpoint of the TC maximum daily rainfall (TMDR) using …

Long noncoding RNAs (lncRNAs) have been reported to regulate diverse tumorigenic
processes. However, little is known about long intergenic non-protein coding RNA 00893 (…

Simple Summary The relationship between inflammation and carcinogenesis, as well as the
response to anti-tumor therapy, is intimate. Atrial natriuretic peptides (ANPs) play a pivotal …

Background and Aim: Measuring postoperative carcinoembryonic antigen (CEA) is
recommended by guidelines to help detecting recurrence of gastric cancer patients. However, the …

Based on high‐resolution numerical simulations, the effects of sea breeze circulation (SBC)
on associated convective initiation and propagation over Hainan Island are investigated. …