User profiles for Qinwei Kim-Wee Zhuang

Qinwei Kim-Wee Zhuang

McGill Univerisity
Verified email at mail.mcgill.ca
Cited by 98

ZMYM2 is essential for methylation of germline genes and active transposons in embryonic development

…, J Sirois, I Hossain, MS Katz, QKW Zhuang… - Nucleic Acids …, 2023 - academic.oup.com
ZMYM2 is a transcriptional repressor whose role in development is largely unexplored. We
found that Zmym2 −/− mice show embryonic lethality by E10.5. Molecular characterization of …

[HTML][HTML] Distinct roles of androgen receptor, estrogen receptor alpha, and BCL6 in the establishment of sex-biased DNA methylation in mouse liver

…, JH Galvez, VS Venkatesh, QK Zhuang… - Scientific reports, 2021 - nature.com
Sexual dimorphism in gene regulation, including DNA methylation, is the main driver of
sexual dimorphism in phenotypes. However, the questions of how and when sex shapes DNA …

[HTML][HTML] Sex chromosomes and sex phenotype contribute to biased DNA methylation in mouse liver

QKW Zhuang, JH Galvez, Q Xiao, N AlOgayil… - Cells, 2020 - mdpi.com
Sex biases in the genome-wide distribution of DNA methylation and gene expression levels
are some of the manifestations of sexual dimorphism in mammals. To advance our …

[HTML][HTML] Genetic variation in the Y chromosome and sex-biased DNA methylation in somatic cells in the mouse

E Batdorj, N AlOgayil, QK Zhuang, JH Galvez… - Mammalian …, 2023 - Springer
Several lines of evidence suggest that the presence of the Y chromosome influences DNA
methylation of autosomal loci. To better understand the impact of the Y chromosome on …

Author Correction: Distinct roles of androgen receptor, estrogen receptor alpha, and BCL6 in the establishment of sex-biased DNA methylation in mouse liver

…, JH Galvez, VS Venkatesh, QK Zhuang… - Scientific Reports, 2021 - nature.com
Figure 5. BCL6, AR, and ESR1 influence DNA methylation at sDMRs.(a) Methylation levels
in male and female Bcl6-LKO (4 females, 4 males) and controls Bcl6-flox mice (6 females, 4 …

[BOOK][B] The influence of the Y chromosome on autosomal DNA methylation

E Batdorj - 2022 - search.proquest.com
… Guillaume Bourque and his student, Qinwei Kim-Wee Zhuang, for analyzing whole genome
… analysis was performed by Qinwei Kim-Wee Zhuang, a student in Dr. Guillaume Bourque’s …

Two Y genes can replace the entire Y chromosome for assisted reproduction in the mouse

Y Yamauchi, JM Riel, Z Stoytcheva, MA Ward - Science, 2014 - science.org
The Y chromosome is thought to be important for male reproduction. We have previously
shown that, with the use of assisted reproduction, live offspring can be obtained from mice …